Français
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
xanthone/crise épileptique
Le lien est enregistré dans le presse-papiers
14 résultats
Anticonvulsant activity of some xanthone derivatives.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of appropriate alkanolamine and amide derivatives of xanthone were prepared and evaluated for anticonvulsant activity using maximal electroshock (MES) and subcutaneous pentylenetetrazole (scMet) induced seizures, and for neurotoxicity (TOX) using the rotorod test on mice and rats. The most
Pharmacological properties of some xanthone derivatives.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of aminoalkanolic derivatives of xanthone were examined in some experimental models of epilepsia, i.e., pilocarpine, aminophylline and pentetrazole-induced seizures. A final objective of this research was to examine the action of these compounds on the central nervous system, namely on
Evaluation of some 2-substituted derivatives of xanthone for anticonvulsant properties.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of alkanolamides and alkanoamines derivatives of xanthone were prepared and evaluated for antiepileptic activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazol seizure threshold (ScMet) assays and for neurotoxicity (TOX). Several analogues from the appropriate
Synthesis and anticonvulsant effects of some aminoalkanolic derivatives of xanthone.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
Synthesis and physicochemical properties of alkanolamine derivatives of xanthone are described. Alkanolamines were synthesized by of the reaction of an appropriate aminoalcohol with corresponding 2-bromomethylxanthones. The obtained compounds 1-13 were evaluated for anticonvulsant activity in the
Central activity of new xanthone derivatives with chiral center in some pharmacological tests in mice.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
The study was designed to investigate some central effects of chiral xanthone derivatives [(R,S)-2-N-(6-chloro-2-xanthonemethyl)-amino-1-propanol - MH-31, R enantiomer - MH-32 and S enantiomer - MH-33] in mice. The effects of these chiral compounds were examined in picrotoxin-induced seizures,
Aminoalkanolic derivatives of xanthone with potential antiepileptic activity.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
Synthesis, physicochemical and anticonvulsant properties of some aminoisopropanoloxy derivatives of 2-xanthone are described. The compounds were prepared by the amination of 2-[(2,3-epoxy)-propoxyl]-xanthone or 2-(3-chloro-2-hydroxy-propoxy)-xanthone. The obtained compounds were evaluated for
Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of new xanthone derivatives with piperazine moiety [1-7] was synthesized and evaluated for their pharmacological properties. They were subject to binding assays for α₁ and β₁ adrenergic as well as 5-HT₁A, 5-HT₆ and 5-HT₇b serotoninergic receptors. Five of the tested compounds were also
Antiarrhythmic and antihypertensive activity of some xanthone derivatives.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
Some of appropriate aminoisopropanoloxy derivatives of 4-xanthone were tested for their effect on circulatory system (protection against adrenaline-, barium-, and calcium chloride-induced arrhythmias, as well as hypotensive activity and acute toxicity). The most prominent hypotensive activity was
Pharmacological properties of some aminoalkanolic derivatives of xanthone.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of appropriate aminoisopropanoloxy derivatives of 2-, 3- or 6-xanthone was synthesized and evaluated for anticonvulsant activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (ScMet) assays and for neurotoxicity (TOX). The most interesting
Neuropharmacological and molecular docking studies of xanthones from Swertia corymbosa.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
Anxiety represents a public health problem consistently found to be the most prevalent class of mental disorders among people of all ages. Xanthones possess many biological properties, including neuroprotective, antioxidant or antidepressant-like. In this study, we aimed to investigate
The influence of some aminoalkanolic xanthone derivatives on central nervous and cardiovascular systems in rodents.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of appropriate aminoalkanolic derivatives 2- or 4-methylxanthone was synthesized and evaluated for anticonvulsant activity in the maximal electroshock seizure (MES) and subcutaneous pentylenetetrazole seizure threshold (scPtz) assays, and for neurotoxicity (TOX). The most interesting result
γ-Mangostin increases serotonin 2A/2C, muscarinic, histamine and bradykinin receptor mRNA expression.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
OBJECTIVE
γ-Mangostin is a xanthone found in the fruit hulls of Garcinia mangostana L., which have long been used in Southeast Asia as a traditional medicine for the treatment of abdominal pain, dysentery, wound infections, fever and convulsions. Recent studies have revealed that γ-mangostin
Evidence of the mechanism of action of Erythrina velutina Willd (Fabaceae) leaves aqueous extract.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
BACKGROUND
Erythrina velutina is traditionally used for sleepiness, convulsions and nervous system excitation in Brazil. Although central effects have been reported for Erythrina velutina, little is known about its mechanism of action.
OBJECTIVE
To investigate the pharmacological evidences of
Anticonvulsant evaluation of aminoalkanol derivatives of 2- and 4-methylxanthone.
Seuls les utilisateurs enregistrés peuvent traduire des articles
Se connecter S'inscrire
A series of 17 new aminoalkanol derivatives of 6-methoxy- or 7-chloro-2-methylxanthone as well as 6-methoxy-4-methylxanthone was synthesized and evaluated for anticonvulsant activity. All compounds were verified in mice after intraperitoneal (ip) administration in maximal electroshock (MES) and
La base de données d'herbes médicinales la plus complète soutenue par la science
- Fonctionne en 55 langues
- Cures à base de plantes soutenues par la science
- Reconnaissance des herbes par image
- Carte GPS interactive - étiquetez les herbes sur place (à venir)
- Lisez les publications scientifiques liées à votre recherche
- Rechercher les herbes médicinales par leurs effets
- Organisez vos intérêts et restez à jour avec les nouvelles recherches, essais cliniques et brevets
Tapez un symptôme ou une maladie et lisez des informations sur les herbes qui pourraient aider, tapez une herbe et voyez les maladies et symptômes contre lesquels elle est utilisée.
* Toutes les informations sont basées sur des recherches scientifiques publiées
