14 torthaí
The invention relates to novel combinations based on anticholinergics, .beta..sub.2-adrenoceptor agonists, PDE 4 Inhibitors, glucocorticoids, and leukotriene-receptor antagonists, process for their production and their use for the treatment of inflammatory diseases, preferably respiratory diseases
BACKGROUND OF THE INVENTION
(a) Field of the Invention
This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n --N.dbd.B]-substituted-piperidines and analogs thereof, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents;
The present invention relates to a combination of an inhaled/oral PDE 4 inhibitor in combination with inhaled anticholinergic bronchodilators (muscarinic receptor antagonists), preferentially Roflumilast or AWD-12-281 and R,R-glycopyrrolate, for symptomatic or prophylactic treatment of respiratory
The present invention describes the combination of topically inhaled medicinal formulations comprising an anticholinergic component and a glucocorticosteroid component and its use in the symptomatic and prophylactic treatment of diseases of the respiratory tract, especially with an obstructive
BACKGROUND OF THE INVENTION
The present invention generally relates to methods of reducing inflammation. More specifically, the invention relates to methods of reducing inflammation using .alpha.7 receptor-binding cholinergic agonists.
Vertebrates achieve internal homeostasis during infection or
CROSS REFERENCES TO RELATED APPLICATIONS
This application claims priority to European Patent Application No. 13176114.0, filed on Jul. 11, 2013 and European Patent Application No. 13194763.2, filed on Nov. 28, 2013, both of which are incorporated herein by reference in their entireties.
BACKGROUND
CROSS REFERENCES TO RELATED APPLICATIONS
This application claims priority to European Patent Application No. 15194660.5, filed on Nov. 16, 2015, which is incorporated herein by reference in its entirety.
BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to powder
CROSS REFERENCES TO RELATED APPLICATIONS
This application claims priority to European Patent Application No. 15194661.3, filed on Nov. 16, 2015, which is incorporated herein by reference in its entirety.
BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to powder
BACKGROUND OF THE INVENTION
(a) Field of the Invention
This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n -N.dbd.B]-substituted-piperidines and analogs thereof, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents; to
BACKGROUND OF THE INVENTION
(a) Field of the Invention
This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n --N.dbd.B]-substituted-piperidines, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents, and to certain
The present invention describes a combination of anticholinergic and .beta. mimetics for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary disease (COPD) and asthma. It further comprises the preparation of this combination in a
The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics.
The compounds of the invention correspond to the following general formula (I): ##STR2## in which: Ar designates:
A phenyl
The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics.
THE COMPOUNDS OF THE INVENTION CORRESPOND TO THE FOLLOWING GENERAL FORMULA (I): ##STR2## in which Ar designates
A phenyl
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to N-substituted 2-aminomethylene-1,3-indanediones and their therapeutic application.
2. Discussion of the Background
The present invention relates to products having the structural formula ##STR2## in which R.sub.1