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anticholinergic/athlasadh

Sábháiltear an nasc chuig an gearrthaisce
14 torthaí
The invention relates to novel combinations based on anticholinergics, .beta..sub.2-adrenoceptor agonists, PDE 4 Inhibitors, glucocorticoids, and leukotriene-receptor antagonists, process for their production and their use for the treatment of inflammatory diseases, preferably respiratory diseases
BACKGROUND OF THE INVENTION (a) Field of the Invention This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n --N.dbd.B]-substituted-piperidines and analogs thereof, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents;

Combination of anticholinergics and inhibitors of phosphodiesterase type 4 for the treatment of respiratory disease

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
The present invention relates to a combination of an inhaled/oral PDE 4 inhibitor in combination with inhaled anticholinergic bronchodilators (muscarinic receptor antagonists), preferentially Roflumilast or AWD-12-281 and R,R-glycopyrrolate, for symptomatic or prophylactic treatment of respiratory

Methods of treating underlying inflammation from COPD or asthma

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
The present invention describes the combination of topically inhaled medicinal formulations comprising an anticholinergic component and a glucocorticosteroid component and its use in the symptomatic and prophylactic treatment of diseases of the respiratory tract, especially with an obstructive

Treatment of inflammation using alpha 7 receptor-binding agonists

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
BACKGROUND OF THE INVENTION The present invention generally relates to methods of reducing inflammation. More specifically, the invention relates to methods of reducing inflammation using .alpha.7 receptor-binding cholinergic agonists. Vertebrates achieve internal homeostasis during infection or

Dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic for administration by inhalation

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
CROSS REFERENCES TO RELATED APPLICATIONS This application claims priority to European Patent Application No. 13176114.0, filed on Jul. 11, 2013 and European Patent Application No. 13194763.2, filed on Nov. 28, 2013, both of which are incorporated herein by reference in their entireties. BACKGROUND

Process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
CROSS REFERENCES TO RELATED APPLICATIONS This application claims priority to European Patent Application No. 15194660.5, filed on Nov. 16, 2015, which is incorporated herein by reference in its entirety. BACKGROUND OF THE INVENTION Field of the Invention The present invention relates to powder

Process for preparing a dry powder formulation comprising an anticholinergic, a corticosteroid and a beta-adrenergic

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
CROSS REFERENCES TO RELATED APPLICATIONS This application claims priority to European Patent Application No. 15194661.3, filed on Nov. 16, 2015, which is incorporated herein by reference in its entirety. BACKGROUND OF THE INVENTION Field of the Invention The present invention relates to powder

Amino-1-[(halophenyl)-lower-alkyl]piperidines

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
BACKGROUND OF THE INVENTION (a) Field of the Invention This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n -N.dbd.B]-substituted-piperidines and analogs thereof, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents; to

Benzoylphenyl lower alkanoyl piperidines

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
BACKGROUND OF THE INVENTION (a) Field of the Invention This invention relates to 1-[(3- or 4-benzoylphenyl)-lower-alkyl]-[(CH.sub.2).sub.n --N.dbd.B]-substituted-piperidines, useful as anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory agents, and to certain

Combination of anticholineric and .beta. mimetics for the treatment of respiratory diseases

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
The present invention describes a combination of anticholinergic and .beta. mimetics for the treatment of respiratory diseases including airway inflammation or obstruction such as chronic obstructive pulmonary disease (COPD) and asthma. It further comprises the preparation of this combination in a

1-(2'-Aroyl eth-1'yl) 2-(4"-acetamido piperazine-1"yl methyl) benzimidazoles and their therapeutical applications

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics. The compounds of the invention correspond to the following general formula (I): ##STR2## in which: Ar designates: A phenyl
The present invention concerns 1-(2'-aroyl eth-1' yl) 2-(4"-acetamido piperazine-1" yl methyl) benzimidazoles, their method of preparation and their application in therapeutics. THE COMPOUNDS OF THE INVENTION CORRESPOND TO THE FOLLOWING GENERAL FORMULA (I): ##STR2## in which Ar designates A phenyl

Therapeutic application of N-substituted 2-aminomethylene-1,3-indanediones

Ní féidir ach le húsáideoirí cláraithe ailt a aistriú
Logáil Isteach / Cláraigh
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to N-substituted 2-aminomethylene-1,3-indanediones and their therapeutic application. 2. Discussion of the Background The present invention relates to products having the structural formula ##STR2## in which R.sub.1
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