creatine/fatigue

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The effect of short-term creatine intake on blood lactic acid and muscle fatigue measured by accelerometer-based tremor response to acute resistance exercise.

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Logáil Isteach / Cláraigh

The purpose of this study was to investigate the effects of short-term creatine intake on muscle fatigue induced by resistance exercise in healthy adolescent men, i.e., lactic acid concentration and wrist and head tremor measured by an accelerometer.Twelve

Inhibition of creatine kinase reduces the rate of fatigue-induced decrease in tetanic [Ca(2+)](i) in mouse skeletal muscle.

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Logáil Isteach / Cláraigh

1. Ca(2+)-phosphate (P(i)) precipitation in the sarcoplasmic reticulum (SR) may cause reduced SR Ca(2+) release in skeletal muscle fatigue. To study this, we inhibited the creatine kinase (CK) reaction with 2,4-dinitro-1-fluorobenzene (DNFB). The hypothesis was that with inhibition of CK,

Fatigue resistance of rat extraocular muscles does not depend on creatine kinase activity.

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Logáil Isteach / Cláraigh

BACKGROUND Creatine kinase (CK) links phosphocreatine, an energy storage system, to cellular ATPases. CK activity serves as a temporal and spatial buffer for ATP content, particularly in fast-twitch skeletal muscles. The extraocular muscles are notoriously fast and active, suggesting the need for

Effect of creatine supplementation during high resistance training on mass, strength, and fatigue resistance in rat skeletal muscle.

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Logáil Isteach / Cláraigh

The aim of this study was to utilize a rodent model of resistance exercise to compare training with creatine supplementation with training alone. We tested the hypothesis that creatine supplementation during high resistance training would result in greater increases in muscle mass, contractile

Incubating isolated mouse EDL muscles with creatine improves force production and twitch kinetics in fatigue due to reduction in ionic strength.

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Logáil Isteach / Cláraigh

BACKGROUND Creatine supplementation can improve performance during high intensity exercise in humans and improve muscle strength in certain myopathies. In this present study, we investigated the direct effects of acute creatine incubation on isolated mouse fast-twitch EDL muscles, and examined how

Effect of oral creatine supplementation on power output and fatigue during bicycle ergometry.

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Logáil Isteach / Cláraigh

Our purpose was to determine the effect of oral creatine supplementation on exercise performance during high-intensity short-duration bicycle sprinting. Power output was recorded for 12 healthy untrained males (age 24.08 +/- 0.53 yr, weight 81.22 +/- 1.32 kg) before and after 5 days of creatine (n =

Is creatine kinase responsible for fatigue? Studies of isolated skeletal muscle deficient in creatine kinase.

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Logáil Isteach / Cláraigh

Creatine kinase (CK) is a key enzyme for maintaining a constant ATP/ADP ratio during rapid energy turnover. To investigate the role of CK in skeletal muscle fatigue, we used isolated whole muscles and intact single fibers from CK-deficient mice (CK(-/-)). With high-intensity electrical stimulation,

Fatigue and changes of ATP, creatine phosphate, and lactate during the 400-m sprint.

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Logáil Isteach / Cláraigh

Fatigue during the 400-m sprint was studied by measuring muscle ATP, creatine phosphate (CP), lactate (M-La), and blood lactate (B-La) in six male runners before and after four experimental sprints (100, 200, 300, and 400 m). During the first 100 m, muscle CP decreased from 15.8 +/- 1.7 to 8.3 +/-

Neuromuscular properties and fatigue in older men following acute creatine supplementation.

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Logáil Isteach / Cláraigh

The purpose of this study was to investigate the effects of creatine (Cr) supplementation in 12 older (65-82 years) men. The subjects were randomly assigned to a Cr or a placebo (P) group. Seven men were supplemented with 5 g of Cr and 5 g maltodextrin four times a day for 5 days (Cr), and 5 men

Muscle fatigue experienced during maximal eccentric exercise is predictive of the plasma creatine kinase (CK) response.

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Logáil Isteach / Cláraigh

Unaccustomed eccentric exercise may cause skeletal muscle damage with an increase in plasma creatine kinase (CK) activity. Although the wide variability among individuals in CK response to standardized lengthening contractions has been well described, the reasons underlying this phenomenon have not

Serum agrin and talin are increased in major depression while agrin and creatine phosphokinase are associated with chronic fatigue and fibromyalgia symptoms in depression.

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Logáil Isteach / Cláraigh

Chronic fatigue and fibromyalgia symptoms frequently occur in major depressive disorder (MDD). The pathophysiology of these symptoms may in part, be ascribed to activated immune pathways, although it is unclear whether muscular factors play a role in their onset. The aim of the present study is to

Effects of creatine loading on electromyographic fatigue threshold in cycle ergometry in college-age men.

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Logáil Isteach / Cláraigh

The purpose of this study was to examine the effects of 5 d of creatine (Cr) loading on the electromyographic fatigue threshold (EMG FT) in college-age men. Sixteen men (age 22.4 +/- 2.6 yr, height 177.4 +/- 6.8 cm, weight 79.5 +/- 10.6 kg; M +/- SD) participated in this double-blind study and were

Creatine supplementation improves performance above critical power but does not influence the magnitude of neuromuscular fatigue at task failure.

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Logáil Isteach / Cláraigh

What is the central question of this study? Does the magnitude of neuromuscular fatigue depend on the amount of work done (W') at task failure when cycling above critical power (CP)? What is the main finding and its importance? Creatine supplementation increases W' and enhances

The effect of creatine supplementation on muscle fatigue and physiological indices following intermittent swimming bouts.

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Logáil Isteach / Cláraigh

We evaluated the effect of Creatine (Cr) supplementation on muscle fatigue and physiological indices after intermittent swimming bouts in trained swimmers. Sixteen healthy non-elite swimmers (19±4 years, 75±12 kg) were randomly assigned into two groups of either Cr supplementation or placebo and

Correlation between biomarkers of creatine metabolism and serum indicators of peripheral muscle fatigue during exhaustive exercise in active men.

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Logáil Isteach / Cláraigh

Exhaustive exercise induces various disturbances of homeostasis, with impaired bioenergetics often associated with strenuous muscular work. However, no study so far validated serum biomarkers of creatine metabolism vs. traditional markers of exhaustive exercise and fatigue. Here, we investigated how

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