monocrotaline/asthenia

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AiltTrialacha cliniciúlaPaitinní

Roghnaigh cineál sórtála

5 torthaí

Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction.

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Logáil Isteach / Cláraigh

We previously demonstrated that diaphragm muscle weakness is present in experimental pulmonary arterial hypertension (PH). However, the nature of this diaphragm weakness is still unknown. Therefore, the aim of this study was to investigate whether changes at the sarcomeric level contribute to

Diaphragm muscle fiber weakness in pulmonary hypertension.

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Logáil Isteach / Cláraigh

BACKGROUND Recently it was suggested that patients with pulmonary hypertension (PH) suffer from inspiratory muscle dysfunction. However, the nature of inspiratory muscle weakness in PH remains unclear. OBJECTIVE To assess whether alterations in contractile performance and in morphology of the

Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension.

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Logáil Isteach / Cláraigh

Patients with pulmonary hypertension (PH) suffer from inspiratory insufficiency, which has been associated with intrinsic contractile dysfunction in diaphragm muscle. Here, we examined the role of redox stress in PH-induced diaphragm weakness by using the novel antioxidant, EUK-134. Male Wistar rats

Pulmonary hypertension in a group of dairy calves.

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Logáil Isteach / Cláraigh

An episode of pulmonary arteritis and sclerosis in twenty 5- to 6-month-old dairy calves was investigated. Sixteen of the calves died acutely, without marked premonitory signs of disease. Four calves evaluated clinically had lethargy, pallor, weakness, tachycardia, tachypnea, and jugular venous

Diaphragm atrophy and contractile dysfunction in a murine model of pulmonary hypertension.

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Logáil Isteach / Cláraigh

Pulmonary hypertension (PH) causes loss of body weight and inspiratory (diaphragm) muscle dysfunction. A model of PH induced by drug (monocrotaline, MCT) has been extensively used in mice to examine the etiology of PH. However, it is unclear if PH induced by MCT in mice reproduces the loss of body

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Herbal & Natural Medicine

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