neurodegenerative diseases/hypoxia

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15 torthaí

Anti-inflammatory Effect of Curcumin, Homotaurine, Vitamin D3 on Human Vitreous in Patients With Diabetic Retinopathy

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Logáil Isteach / Cláraigh

Diabetic retinopathy is one of the most common complications of diabetes mellitus and is a leading cause of vision loss and blindness in the working-age population worldwide. DR is being recognized as a neurodegenerative disease of the retina as opposed to previously considered solely as a

The Long-term Consequences After Traumatic Brain Injury in the Elderly

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Logáil Isteach / Cláraigh

A database of over 1200 patients will be created by the retrospective capture of the following data in UZ Leuven database: Injury mechanisms data: In order to create a map of injury patterns, severity and criteria that allow for identifying which accident circumstances ageing adults should

Simvastatin in Secondary Progressive Multiple Sclerosis

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Logáil Isteach / Cláraigh

Approximately 60% of those affected with relapsing-remitting MS (RRMS) enter a SPMS stage after a median interval of 10 to 15 years, where disability accumulates gradually in the absence of relapses. A smaller proportion (15%), run a progressive course from onset (primary progressive (PP) MS). The

Utilization of the Ketogenic Diet in Patient With Relapsing Remitting MS

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Logáil Isteach / Cláraigh

The purpose of this study is to see if a high fat, low carbohydrate diet is safe and how it effects post trial diet habits, physique, and disease course in patients with relapsing remitting multiple sclerosis. In particular, multiple sclerosis is a neurodegenerative disorder that is characterized by

Cerebrovascular Changes in Multiple Sclerosis Patients

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Logáil Isteach / Cláraigh

Multiple sclerosis (MS) MS is a chronic disease containing the inflammatory, demyelinating, anddegenerative processes of the central nervous system[FrischerJMet al, 2009]. The inflammation, microglial activation, astrocyticgliosis, demyelination, and somewhat axonal loss inwhite matter and grey

Predicting Postoperative Delirium Using EEG, Genetics and Neurobiomarkers of Cerebral Injury

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Logáil Isteach / Cláraigh

POD is defined as a "fluctuating disturbance in attention that represents an acute change from baseline, accompanied by disturbed cognition or perception, and not due to a pre-existing neurocognitive disorder or occurring in the context of a severely reduced arousal level". Depending on the type of

Effect of Dexmedetomidine on Postoperative Delirium Inflammasome Activation Inhibition

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Logáil Isteach / Cláraigh

Delirium is an acute and subacute comorbid syndrome characterized by decreased awareness and cognitive dysfunction accompanied by attention deficit. It varies from 20% to 80% in patients entering the ICU. If delirium occurs in the intensive care unit, complications such as unintended intubation,

The White Blood Cell Reactivity Following Surgical Trauma and Associated Regulatory Mechanisms.

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Logáil Isteach / Cláraigh

Surgical trauma causes release of damage-associated molecular patterns (DAMPs) and other alarmines (e.g. HMGB-1) targeting receptors on local cells of the innate immune system, such as macrophages. This cellular response to trauma is followed by a rapid release of an array of inflammatory mediators

Post-surgery Systemic Inflammation and Neuro-immune Interactions

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Logáil Isteach / Cláraigh

Surgical trauma causes release of damage-associated molecular patterns (DAMPs) and other alarmines (e.g. high mobility group box (HMGB-1)) targeting receptors on local cells of the innate immune system, such as macrophages. This cellular response to trauma is followed by a rapid release of an array

Bioenergetics and Protein Metabolism in Sporadic Amyotrophic Lateral Sclerosis

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Logáil Isteach / Cláraigh

The investigators will study fibroblasts derived from sporadic ALS patients. Clinical parameters will be collected such as sex, age, age of onset, clinical presentation, electrophysiological an respiratory parameters, treatments. Patients and controls derived fibroblasts will be amplified and

Role of Hypoxia Ans Sleep Fragmentation in Alzheimer's Disease. and Sleep Fragmentation.

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Logáil Isteach / Cláraigh

As AD and OSA have a bidirectional relationship, OSA causes cerebral hypoxia and sleep fragmentation favouring the deposition of AB and AD causes alterations in sleep quality, investigators will develop a comprehensive project with human patients and an animal model of AD with sleep fragmentation

Genes, Exercise, Neurocognitive and Neurodegeneration: Community-Based Approach

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Logáil Isteach / Cláraigh

Although anticholinesterase therapies have greatly improved the symptomatic treatment of Alzheimer's disease (AD), they have not been demonstrated to significantly slow the disease progression; and amyloid-directed therapies have produced disappointing results. A promising evidence-based and

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement.

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Logáil Isteach / Cláraigh

Cardiovascular diseases remain the major cause of mortality and morbidity in industrialised countries. Their prevalence increases steeply as consequence of the aging of the population in these countries. Curiously, cardiovascular and neurodegenerative diseases share common aging pathological

Growth and Intelligence Outcome in Children Who Developed Perioperative Desaturation

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Logáil Isteach / Cláraigh

Material and methods A historical and concurrent follow up study was conducted at Songklanagarind Hospital, an 853-bed tertiary care hospital in southern Thailand, after approval by the Ethics Committee, Prince of Songkla University at November 15th, 2012. Written informed consent was signed by all

GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS)

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Logáil Isteach / Cláraigh

Background 1. In the early 1990s Genervon hypothesized that Central Nervous System / Peripheral Nervous systme (CNS/PNS) and rare motoneuron diseases and disorders involve the interplay of a highly complex, multifactorial process of many non-dominant effectors in an interactive dynamic network.

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Herbal & Natural Medicine

An bunachar luibheanna míochaine is iomláine le tacaíocht ón eolaíocht

Oibreacha i 55 teanga
Leigheasanna luibhe le tacaíocht ón eolaíocht
Aitheantas luibheanna de réir íomhá
Léarscáil GPS idirghníomhach - clibeáil luibheanna ar an láthair (ag teacht go luath)
Léigh foilseacháin eolaíochta a bhaineann le do chuardach
Cuardaigh luibheanna míochaine de réir a n-éifeachtaí
Eagraigh do chuid spéiseanna agus fanacht suas chun dáta leis an taighde nuachta, trialacha cliniciúla agus paitinní

Clóscríobh symptom nó galar agus léigh faoi luibheanna a d’fhéadfadh cabhrú, luibh a chlóscríobh agus galair agus comharthaí a úsáidtear ina choinne a fheiceáil.
* Tá an fhaisnéis uile bunaithe ar thaighde eolaíoch foilsithe