Leathanach 1 ó 80 torthaí
FIELD OF THE INVENTION
The present disclosure relates to methods for the detection and quantization of urinary polyamines and compositions for use therein. The methods and compositions described herein are useful in diagnosis of prostate cancer in patient.
BACKGROUND OF THE INVENTION
Prostate cancer
FIELD OF THE INVENTION
The present invention relates to the field of cancer therapy. In particular, the invention provides novel polyamine compounds and pharmaceutical compositions for reducing or preventing toxic side effects of radiotherapy and cancer chemotherapeutic agents.
BACKGROUND OF THE
STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable.
TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and
TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and other diseases caused by abnormal cell proliferation, as well as improved methods for
STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable.
TECHNICAL FIELD
This invention is directed to cycloalkyl-substituted polyamine analog compounds, particularly cyclopropyl-containing polyamine analog compounds, useful as chemotherapy treatments in cancer and
The marking of biomolecules and the follow-up of biological phenomena require the designing of fluorescent probes which have become indispensable tools for structural and functional studies of biological media.
A fluorescent probe is a conjugated molecule, consisting of a fluorophore or fluorochrome
BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of cancer biology and medicine. More particularly, it concerns methods for the diagnosis, prevention, and treatment of carcinomas and risk factors thereof.
II. Description of Related
FIELD OF THE INVENTION
The present invention relates to the field of cancer treatment and, more particularly, to polyamines which, due to their special structure, preferentially enter cells having an upregulated polyamine transport system.
BACKGROUND OF THE INVENTION
Polyamines are essential growth
FIELD OF THE INVENTION
The present invention relates to the field of cancer treatment and, more particularly, to polyamines which, due to their special structure, preferentially enter cells having an upregulated polyamine transport system.
BACKGROUND OF THE INVENTION
Polyamines are essential growth
TECHNICAL FIELD
This invention pertains to polyamine compounds, including polyamine/guanidine and polyamine/biguanide compounds, useful for treatment of cancer and/or parasitic infections, and for inhibition of lysine-specific demethylase.
BACKGROUND
Polyamines are found in both eukaryotic and
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
REFERENCE TO AN APPENDIX
Not applicable.
TECHNICAL FIELD
This invention relates to porphyrin-polyamine conjugate compounds used for treatment of cancer and other diseases.
BACKGROUND OF THE INVENTION
Cancer is the third
FIELD OF INVENTION
This invention relates to polyamine compounds and more particularly to tetraamine derivatives and their use as N-Methyl-D-Aspartate (NMDA) inhibitors for therapeutic treatment of neurodegenerative disorders, such as stroke, Alzheimer's disease, other neurodegenerative disorders,
STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable
TECHNICAL FIELD
This invention relates to therapeutic compositions in which a cytostatic or cytocidal compound, such as a polyamine analog or a quinone, is conjugated to a polypeptide recognized and cleaved by
STATEMENT OF RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH
Not applicable
TECHNICAL FIELD
This invention relates to therapeutic compositions in which a cytostatic or cytocidal compound, such as a polyamine analog or a quinone, is conjugated to a polypeptide recognized and cleaved by
FIELD OF THE INVENTION
The present invention relates to the field of cancer therapy. In particular, the invention provides novel compositions and methods for reducing or preventing toxic side effects of radiotherapy and cancer chemotherapeutic agents using polyamine effector molecules locally