Chemical Communications 2014-May
Multifunctional squalene-based prodrug nanoparticles for targeted cancer therapy.
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कीवर्ड
सार
Fluorescent and biotinylated squalene-gemcitabine prodrug nanoparticles exhibiting high drug payloads have been prepared and successfully used to target different cancer cell lines, resulting in increased cell uptake and improved anticancer efficiency, which represents the first targeted system derived from the squalenoylation approach.