Pharmacological properties of a protease from ficus hispiad linn.

A sulphydryl plant protease present in the latex of Ficus hispida Linn affects hatematological values in mice. The isolated protease was found to increase clotting time and erythrocyte sedimentation rate while haemoglobin conten, RBC count and WBC count were decreased in a dose dependent manner. Ointment containing 1.0% (w/w) hispidain in washable ointment base showed good wound healing property in mice. The protease also possesses mild anti inflammatory activity.