पृष्ठ 1 से 35 परिणाम
FIELD OF THE INVENTION
The invention relates to the nucleic acid of a novel megakaryocyte-associated tyrosine kinase (MATK)-related gene variant, the polypeptide encoded thereby, the preparation process thereof, and the uses of the same in diagnosing diseases associated with the deficiency of human
FIELD OF THE INVENTION
The invention relates to the nucleic acid of a novel megakaryocyte-associated tyrosine kinase (MATK)-related gene variant, the polypeptide encoded thereby, the preparation process thereof, and the uses of the same in diagnosing diseases associated with the deficiency of human
BACKGROUND OF THE INVENTION
Receptor tyrosine kinases (RTKs) are transmembrane signaling proteins that transmit biological signals from the extracellular environment to the interior of the cell. The regulation of RTK signals is important for regulation of cell growth, differentiation, axonal growth,
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A portion of the disclosure of this patent document contains material, which is subject to copyright protection. The copyright owner has no objection to the facsimile reproduction by anyone of the patent document or the patent disclosure, as it appears in the Patent and Trademark
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the diagnosis of cancer, and particularly to lung cancer detection by optical analysis of body fluids that uses fluorescence spectroscopy to examine samples of blood, urine, and/or sputum to diagnose cancer of the
FIELD OF THE INVENTION
The present invention relates to thiourea/amidine functionalized tyrosine kinase inhibitors modified with gold, platinum, and other precious metal compounds. The thiourea/amidine-modified 3-chloro-4-fluoroanilino-quinazoline derivatives were studied as carrier ligands in
BACKGROUND OF THE INVENTION
Cancer is the second leading cause of death in the United States, exceeded only by heart disease. (Cancer Facts and Figures 2004, American Cancer Society, Inc.) Despite recent advances in cancer diagnosis and treatment, surgery and radiotherapy may be curative if a cancer
CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a national phase entry under 35 U.S.C .sctn.371 of International Application No. PCT/CN2013/000720 filed Jun. 20, 2013, which is hereby incorporated herein by reference.
TECHNICAL FIELD
The present disclosure pertains to the medical
The present invention relates to a method for treating solid cancers including non-small cell lung cancer, pancreatic, bladder, breast and ovarian cancer, prostate cancer, as well as advanced biliary tract cancers comprising administering at least one antineoplastic agent such as a nucleotide
TECHNICAL FIELD
This invention relates to heterocyclic pyrimidine compounds that modulate mutant-selective epidermal growth factor receptor (EGFR) kinase activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Stage application of PCT/CN2014/082084, filed Jul. 11, 2014, which claims priority from International application PCT/CN2013/079232, filed Jul. 11, 2013.
TECHNICAL FIELD
This invention relates to heterocyclic pyrimidine compounds
The present invention relates to a method of treating patients suffering from cancers driven by deregulated Human Epidermal Growth Factor Receptor (HER/Human EGFR) such as, but not limited to, non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), breast cancer,
FIELD OF THE INVENTION
The invention relates generally to proteins and genes involved in cancer, and to the detection, diagnosis and treatment of cancer.
BACKGROUND OF THE INVENTION
Many cancers are characterized by disruptions in cellular signaling pathways that lead to aberrant control of cellular
FIELD OF THE INVENTION
The invention relates generally to proteins and genes involved in cancer, and to the detection, diagnosis and treatment of cancer.
BACKGROUND OF THE INVENTION
Many cancers are characterized by disruptions in cellular signaling pathways that lead to aberrant control of cellular
BACKGROUND OF THE INVENTION
Advanced non-small cell lung cancer (NSCLC) is the most common cause of cancer death for both men and women in the United States. In 2005 it is estimated that there will be over 170,000 new cases of NSCLC. Most patients are diagnosed with advanced disease and the median