Applied and Environmental Microbiology 2004-Aug
Cyanobacterial protease inhibitor microviridin J causes a lethal molting disruption in Daphnia pulicaria.
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Laboratory experiments identified microviridin J as the source of a fatal molting disruption in Daphnia species organisms feeding on Microcystis cells. The molting disruption was presumably linked to the inhibitory effect of microviridin J on daphnid proteases, suggesting that hundreds of further cyanobacterial protease inhibitors must be considered potentially toxic to zooplankton.