Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 2008-May
[Optimization for formulation matrix proportion of xiangyu cataplasm by uniform design].
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OBJECTIVE
To optimize the matrix formulation of cataplasm used to cure infantile diarrhea.
METHODS
The optimum proportion of matrix for the preparation technology process of cataplasm was selected by uniform design and SPSS regression analysis. A check-up for adhibition , peeling strength, nonflowing, content of cream was founded.
RESULTS
The best matrix's prescription gelatin: CMC-Na: PANA: kaolin: aluminum trichloride: citric acid: PVP K-30: PEG400: trimethylene glycol: tween-80 was 0.25 : 0.1 : 0.2 : 1.5 : 0.4 : 0.6 : 0.8 : 2 : 1 : 0.5.
CONCLUSIONS
The preparation technique of cataplasm is feasible, and its quality is steerable, it is a safe and effective transdermal-drug delivery system.
