canavanine/sarcoma

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A major cytoplasmic glucose-regulated protein is associated with the Rous sarcoma virus pp60src protein.

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Prijava Registriraj se

Previous studies have established that glucose deprivation of murine cells suppresses the synthesis of an Mr = 85,000 polypeptide. A protein of approximately the same molecular weight has been found to be associated with the transforming protein of Rous sarcoma virus, pp60src. The present study

L-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human tumor cell lines.

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L-Canavanine (L-CAV) is a naturally occurring L-arginine analog that induces the formation of non-functional proteins in a variety of organisms. Previous studies have shown that L-CAV is cytotoxic for several human tumor cell lines. In this study, we have evaluated the cytotoxicity of L-CAV for both

Characterization of viral polyproteins in cells transformed and producing Moloney murine sarcoma virus-124.

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The viral proteins of Moloney murine sarcoma virus-transformed mouse cells (G8-124), that overproduce the sarcoma virus relative to helper leukemia virus, were examined by immunoprecipitation, sizing by gel electrophoresis and peptide mapping. Using antisera to the viral core proteins, a

Effect of canavanine on murine retrovirus polypeptide formation.

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Canavanine is an arginine analog which is widely used to inhibit proteolytic processing of viral polyproteins. Certain results obtained with canavanine have suggested that it may have other effects. Therefore, we examined the effects of canavanine on the cell-free synthesis of murine retrovirus

[Cryptococcus neoformans chemotyping. Review of the literature. New epidemiologic data on cryptococcosis. Our experience with the use of C.G.B. media in the study of this yeast].

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The purpose of this work was to collect the main information from the literature about the biotyping of Cryptococcus neoformans. The more up-to date research concerning the epidemiology of cryptococcosis comprising quite a few articles, mainly after the advent of AIDS, was also reviewed. The

Characterization of type C virus induction by amino acid analogs.

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Several amino acid analogs were tested for their ability to induce type C virus from a cloned Balb/c mouse cell line transformed by Kirsten sarcoma virus. O-Methylthreonine and hydroxynorvaline, analogs of isoleucine and threonine, respectively, were found to induce type C virus with the host range

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