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cardiomegaly/panaks

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ČlanciKlinička ispitivanjaPatenti
7 rezultatima

[Relationship between the inhibitory effects of PNS on cardiac hypertrophy and its action on neurohormonal factor].

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OBJECTIVE To study the effects of total saponins of Panax notoginseng (PNS) on the overall model and vitro model of cardiac hypertrophy, and investigate the mechanism of its action. METHODS Cardiac hypertrophy of rats due to pressure overload was induced by constricting of abdominal aorta. The rats
Notoginsenoside R1, a unique constituent from the root of Panax notoginseng, exerts anti-inflammatory, anti-oxidative and anti-apoptotic properties. The purpose of this study was to assess the contribution of the anti-inflammatory effects of R1 to the amelioration of isoproterenol (ISO)-induced
Leptin is a 16-kDa peptide primarily derived from white adipocytes and is typically elevated in plasma of obese individuals. Although leptin plays a critical role in appetite regulation, leptin receptors have been identified in numerous tissues including the heart and have been shown to directly

Roles and mechanisms of ginseng in protecting heart.

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Ginseng, the root of Panax ginseng C. A. Mayer, has long been used clinically in China to treat various diseases. Multiple effects of ginseng, such as antitumor, antiinflammatory, antiallergic, antioxidative, antidiabetic and antihypertensive have been confirmed by modern medicine. Recently, the

Preventive effects of North American ginseng (Panax quinquefolius) on diabetic retinopathy and cardiomyopathy.

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Ginseng (Araliaceae) has multiple pharmacological actions because of its diverse phytochemical constituents. The aims of the present study are to evaluate the preventive effects of North American ginseng on diabetic retinopathy and cardiomyopathy and to delineate the underlying mechanisms of such
There is increasing evidence for a beneficial effect of ginseng on cardiac pathology. Here, we determined whether North American ginseng can modulate the deleterious effects of the β-adrenoceptor agonist isoproterenol on cardiac hypertrophy and function using in vitro and in vivo approaches.
BACKGROUND A major challenge in the treatment of heart failure is the ability to reverse already-established myocardial remodeling and ventricular dysfunction, with few available pharmacological agents prescribed for the management of heart failure having demonstrated successful reversal of the
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