PET/CT Imaging with administration of [F-18] RGD-K5

Carotid Arteries

PET Imaging/scan with [F-18] RGD-K5, PET Imaging/scan with RGD-K5, PET Imaging/scan with K5

PET/CT Imaging with [F-18] RGD-K5

Cedars-Sinai Medical Center

TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study

An Exploratory, Phase II, Open Label, Single-Center, Non-Randomized Study Of [F-18] RGD-K5 Positron Emission Tomography (PET) In Participants With Carotid Artery Stenosis

To assess the uptake of [F-18] RGD-K5 by carotid plaque with PET/MRI imaging in participants prior to carotid endarterectomy and thereby determine if carotid plaque that causes significant stenosis [in participants being considered for carotid endarterectomy (CEA)] is characterized by increased integrin expression and enhanced angiogenesis.

to collect safety data of [F-18] RGD-K5 when given with PET/MRI imaging

Balaji Tamarappoo

Staff, Cardiac Imaging

Ostomy

Combining Ostom-I With Abstats Sensors to Improve Prediction of Ostomy Output

Defined as area under the curve for a plot of intestinal rate vs. time

Defined as maximum intestinal rate achieved in preceding 5 hours

Christopher Almario

Health Services Research Scientist

11 Heath and Technologies Limited

Ultrasound guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.

Laparoscopic guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.

No TAP block performed
Placebo: The usual intraoperative and postoperative pain control; NO TAP block performed

PLACEBO

Ultrasound guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.
US TAP Bupivacaine/Epinephrine: Ultrasound guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.

US TAP Bupivacaine/Epinephrine

Laparoscopic guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.
Lap TAP Bupivacaine/Epinephrine: Laparoscopic guided bupivacaine 0.25% with epinephrine 1:400k will be injected to the transversus abdominis plane.

Lap TAP Bupivacaine/Epinephrine

Total

Sex: Female, Male

Race (NIH/OMB)

American Society of Anesthesiologist Classification grading performed by anesthesiologist prior to surgery
Grading per standard ASA guidelines:
ASA class I - normal healthy adult ASA class II - patients with mild systemic disease ASA class III - patients with severe systemic disease ASA class IV - patients with severe systemic disease that is a constant threat to life ASA class V - a moribund patient that is not expected to survive

American Society of Anesthesiologist Classification

Compare ultrasound-guided block of the transversus abdominis plane (TAP) vs laparoscopic-guided TAP block, versus no TAP block on opioid consumption in the first 24 hours. Patients hospital chart was queried for use of any intravenous opioid in the first 24 hours after surgery including fentanyl or hydromorphone and conversion to morphine per standard opioid dose conversion. Total morphine equivalents then summed for the 24 hour postoperative period and compared between groups.

Morphine Requirement

Overall Study

Dr. Karen Zaghiyan

Crohn's Disease

Inflammatory Bowel Disease

Postoperative Pain

The usual intraoperative and postoperative pain control; NO TAP block performed

Placebo

A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques

A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Technique Versus Laparoscopic Transversus Abdominis Plane Nerve Block Technique Versus No Block on Postoperative Opioid Consumption After Major Colorectal Surgery

cedrela/nausea

TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study

Combining Ostom-I With Abstats Sensors to Improve Prediction of Ostomy Output

A Comparison of Ultrasound Guided Transversus Abdominis Plane Nerve Block Techniques

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