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chiro inositol/seizures

Veza se sprema u međuspremnik
ČlanciKlinička ispitivanjaPatenti
6 rezultatima

Restoration of brain myo-inositol levels in rats increases latency to lithium-pilocarpine seizures.

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Prijava Registriraj se
Lithium pretreatment in rats potentiates the epileptogenic effects of pilocarpine and other cholinergic agonists. In order to determine if this effect of lithium could be reversed by myo-inositol, rats were pretreated with intracerebroventricular (ICV) injections of myoinositol, artificial CSF or

D-chiro inositol phosphoglycans in preeclampsia: Where are we, where are we going?

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Preeclampsia results from a complex interaction between immunological alterations, endothelial dysfunction, and insulin resistance. Inositol second messengers are known to be involved in metabolic signaling and are highly expressed during preeclampsia. In the past two decades, several studies were

Neuropharmacological effects of d-pinitol and its possible mechanisms of action.

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The aim was to evaluate the diuretic and neuropharmacological actions of d-pinitol and describe a possible mechanism of action. The diuretic effects of d-pinitol were evaluated using mice placed in metabolic cages. The sedative, anxiolytic-like, antidepressant-like, and anticonvulsant effects of

Behavioral evidence for the existence of two pools of cellular inositol.

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Lithium reduces brain inositol levels by inhibiting inositol monophosphatase. In a previous study it was found that administration of pilocarpine to Li-treated rats causes limbic seizure behavior which can be reversed by i.c.v. myo-inositol but not chiro-inositol, suggesting that this behavior is

Myo-inositol attenuates two specific behavioral effects of acute lithium in rats.

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Prijava Registriraj se
Acute and chronic lithium treatment reduces levels of brain myo-inositol in rats. Several biological effects of lithium can be reversed in vitro by addition of myo-inositol. The ability of myo-inositol to reverse behavioral effects of lithium was tested using chronic inositol administration or acute
Lithium (Li) reduces brain inositol levels by inhibiting the enzyme inositol monophosphatase. The enzyme inositol-1-phosphatase was measured in human red blood cells of controls, Li-free bipolar patients, and Li-treated bipolar patients and was found to be reduced by 80% in Li-treated bipolars, thus
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