chronic periodontitis/albumin

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[Variations in protein concentration and albumin/globulin ratio of whole unstimulated saliva obtained from healthy people and patients with chronic periodontitis].

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OBJECTIVE We detected and analyzed the clinical values of total protein (TP), albumin (ALB), globulin (GLB), and ALB/GLB ratio (A/G) of whole unstimulated saliva of healthy people to determine the time of day when saliva composition is relatively stable. We compared the protein concentration and A/G

Gingival crevicular fluid IL-6, tPA, PAI-2, albumin levels following initial periodontal treatment in chronic periodontitis patients with or without type 2 diabetes.

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OBJECTIVE To evaluate initial periodontal treatment effects on gingival crevicular fluid (GCF) interleukin-6 (IL-6), tissue-type plasminogen activator (tPA), plasminogen activator inhibitor-2 (PAI-2), albumin levels in type 2 diabetic patients. METHODS GCF samples were collected from 20 type 2

A study to evaluate the correlation of serum albumin levels with chronic periodontitis.

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BACKGROUND Periodontitis is a chronic inflammatory disease caused by bacterial infection of the supporting tissues around the teeth. Serum albumin levels might be the practical marker of general health status. Albumin concentration is associated with nutrition and inflammation. OBJECTIVE The aim of

Quantitative estimation and correlation of serum albumin levels in clinically healthy subjects and chronic periodontitis patients.

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OBJECTIVE The aim of this study was to evaluate the relationship between periodontal disease and general health status in adults using the serum albumin concentration. METHODS A total of 100 patients of both genders with age range of 40 to 70 years were included in the study. Patients were divided

Comparative analysis of gingival crevicular fluid β-glucuronidase levels in health, chronic gingivitis and chronic periodontitis.

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OBJECTIVE Current methods available for periodontal disease diagnosis are seriously deficient in terms of accuracy, in the ability to predict ongoing or future disease activity and indeed in determining whether previously diseased sites are in an arrested phase or still active. One area that is

Ischemia Modified Albumin: A Novel Systemic Indicator of Periodontal Tissue Damage.

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BACKGROUND Ischemia-modified albumin (IMA) is a systemic indicator of inflammatory diseases and is suggested as an oxidative stress marker. OBJECTIVE To determine the IMA and high-sensitivity C-reactive protein (hsCRP) serum levels for patients with chronic periodontitis (CP) and to evaluate the

Elevated conversion of alpha-2-macroglobulin to the complexed form in gingival crevicular fluid from adult periodontitis patients.

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The broad spectrum protease inhibitor, alpha 2-macgrolobulin (alpha 2M), is one of the host's principal regulators of both endogenous and exogenous proteases and is likely to have an important role in the regulation of proteolytic activity at inflammatory sites. We have determined the amount of

Glycated albumin and calprotectin levels in gingival crevicular fluid from patients with periodontitis and type 2 diabetes.

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BACKGROUND Patients with diabetes mellitus (DM) have a high prevalence of periodontitis. Periodontitis in these patients is characterized by severe inflammation and tissue breakdown, and its diagnosis is important for cures of periodontitis and DM. The purpose of this study is to investigate the

Proteolysis and utilization of albumin by enrichment cultures of subgingival microbiota.

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Subgingival dental plaque consists mainly of microorganisms that derive their energy from amino acid fermentation. Their nutrient requirements are met by the subgingival proteolytic system, which includes proteases from microorganism and inflammatory cells, and substrate proteins from sulcus

A new albumin-depletion strategy improves proteomic research of gingival crevicular fluid from periodontitis patients.

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OBJECTIVE Gingival crevicular fluid (GCF), the inflammatory infiltrate within the crevicular sulcus, is of great importance for diverse processes in the oral cavity and has a high impact in oral sciences. It is assumed to serve as a source of biomarkers for systemic or periodontal diseases and

Role of gingipains in growth of Porphyromonas gingivalis in the presence of human serum albumin.

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Porphyromonas gingivalis, a bacterium associated with active chronic periodontitis lesions, produces several proteolytic enzymes that are thought to be involved in host colonization, perturbation of the immune system, and tissue destruction. The aim of the present study was to investigate the

Chronic Periodontitis Case Definitions and Confounders in Periodontal Research: A Systematic Assessment.

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Case definitions and criteria of periodontal diseases are not yet consistent worldwide. This can affect the accuracy of any comparison made between two studies. This study determines which are the most common chronic periodontitis case definitions as well as confounding variables that have been

Patterns of salivary analytes provide diagnostic capacity for distinguishing chronic adult periodontitis from health.

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Salivary biomarker discovery requires identification of analytes with high discriminatory capacity to distinguish disease from health, including day-to-day variations that occur in analyte levels. In this study, seven biomarkers associated with inflammatory and tissue destructive processes of

Comparative proteomic analysis of whole saliva from chronic periodontitis patients.

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Chronic periodontal disease is a chronic inflammatory process affecting tooth supporting tissues in the presence of pathogenic bacterial biofilm. There is some evidence for changes in the protein composition of whole saliva from chronic periodontitis patients, but there have been no studies using a

Relationship between periodontal outcomes and serum biomarkers changes after non-surgical periodontal therapy.

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The systemic effect of chronic periodontitis (CP) has been suggested by several studies as an etiologic factor and modulator of diseases based on the changes in the inflammatory marker levels. This study aimed to investigate the relationship between the changes in clinical periodontal outcomes and

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