Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, 2-hydroxypropanoic acid 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioicacid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone. Topical application of compositions comprising 2-hydroxycarboxylic acid and/or related compounds has been found to alleviate or improve skin lines; blotches; blemishes; nodules; wrinkles; pigmented spots; atrophy; precancerous lesions; elastotic changes characterized by leathery, coarse, rough, dry and yellowish skin; and other skin changes associated with intrinsic aging or skin damages caused by extrinsic factors such as sunlight, radiations, air pollution, wind, cold, dampness, heat, chemicals, smoke and cigarette smoking. Topical applications of such compositions have also been found to improve the overall qualities of nail and hair affected by intrinsic aging or damaged by extrinsic factors.

Tristrata Technology, Inc.

Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid

Our invention is a mixture of carboxylic acids: citric acid, succinic acid, fumaric acid and malic acid, and any possible combinations thereof. This product is used orally or also intravenously, in the treatment of patients with chronic renal failure, hyperammonemia or human conditions having negative nitrogen balance. This product is beneficial in decreasing the serum values of urea and serum ammonium, while promoting by transamination of the oxalacetate formed via succinate, fumarate and malate, the biosynthesis of non-essential amino acids; by transamination of the alpha ketoglutarate formed via citrate, it generates glutamic acid and related amino acids such as glutamine. This treatment prevents, preserves and even improves kidney function. In other patients it delays deterioration of renal function and the urgent need for renal replacement therapy. In others, it is used as a supplemental renal replacement treatment to improve the patient's quality of life and improve laboratory parameters.

Hernandez Miramontes; Jorge Antonio

Mixture of carboxylic acids for treating patients with kidney failure

An object of the present invention is to provide an emulsification-stable pesticidal composition having ant-control, rotcontrol and mildew-control effects. Another object of the present invention is to provide a composition having pesticidal effects, and particularly antimicrobial effects, for protecting industrial materials such as wood, pulp, paper, fibers, adhesives, films subject to deterioration (rotting) and contamination by insects and particularly by microorganisms. A pesticidal composition is used that comprises an emulsification stabilizer selected from the group consisting of lactic acid, glycolic acid, citric acid, succinic acid, benzoic acid and a mixture thereof, a fungicide like 2-(thiazol-4ine)benzimidazole; a further triazole-based fungicide component, a pyrethroid insecticide component or a (thia) nicotinyl insecticide or another insecticide component, a mixed solvent comprising a glycol-based solvent and methyl pyrrolidone, and a surfactant.

citric acid/atrophy

Alleviating signs of dermatological aging with glycolic acid, lactic acid or citric acid

Mixture of carboxylic acids for treating patients with kidney failure

Emulsifications-stable pesticidal composition

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