Stranica 1 iz 234 rezultatima
OBJECTIVE
The present study was designed to investigate the potential association between the 981C>T polymorphism in protein tyrosine phosphatase 1B (PTP-1B) and coronary artery disease (CAD).
METHODS
We conducted a hospital-based case-control study with 864 CAD patients and 1008 controls to explore
Recent studies showed that the serum alkaline phosphatase is an independent predictor of the coronary artery disease (CAD). In this work, we aimed to summarize the association between three phosphatase related single nucleotide polymorphisms (rs12526453, rs11066301 and rs3828329) and the risk of CAD
OBJECTIVE
Whether gamma-glutamyl transferase (GGT) or alkaline phosphatase (ALP) is a better prognostic marker in patients with coronary heart disease (CHD) remains unknown. The aim of this study was to compare the prognostic value of GGT and ALP in patients with CHD.
RESULTS
This study included
Some genetic association studies tried to investigate potential associations of phosphatase and actin regulator 1 (PHACTR1) polymorphisms with coronary artery disease (CAD). However, the results of these studies were not consistent. Thus, we performed the present meta-analysis to We have previously shown that the deficiency of the gut enzyme intestinal alkaline phosphatase (IAP) is associated with type 2 diabetes mellitus (T2DM) in humans, and mice deficient in IAP develop the metabolic syndrome, a precipitant of T2DM and ischemic heart disease (IHD). We OBJECTIVE
Genome-wide association studies identified novel loci in
PLPP3 (phospholipid
phosphatase 3) that associate with
coronary artery disease risk independently of traditional risk factors.
PLPP3 encodes LPP3 (lipid phosphate
phosphatase 3), a cell-surface
Alkaline phosphatase and myeloperoxidase was examined in patients with chronic ischemic heart disease and myocardial infarction. It was established that patients with myocardial infarction showed high values of alkaline phosphatase while the values of myeloperoxidase were low. Dynamic evaluation of
OBJECTIVE
Tartrate-resistant acid phosphatase (TRACP)-5b and osteoprotegerin (OPG) are specific and sensitive markers of bone resorption in patients with rheumatoid arthritis (RA) and chronic kidney disease (CKD). The TRACP-5b level is associated with the severity of RA and CKD, while the OPG level
OBJECTIVE
The serum alkaline phosphatase (ALP) level has shown to be a prognostic factor in myocardial infarction and peripheral vascular disease by its promoting effect on vascular calcification. A few recent studies also showed that elevated ALP levels were associated with mortality and
BACKGROUND
The evidence on the association between alkaline phosphatase (ALP) and prognosis of patients with coronary artery disease (CAD) is limited. The aim of this study was to assess the association of ALP with the risk of mortality or coronary events in patients with CAD.
METHODS
The study
OBJECTIVE
To investigate the association of alkaline phosphatase (ALP) levels with the risk of the composite end point of cardiovascular disease (CVD), and all-cause mortality as well as each of them separately.
METHODS
Prospective cohort study.
METHODS
Within the framework of the Tehran Lipid and
OBJECTIVE
Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelium leads to arterial calcification in mice. The purpose of this study was to examine the effect of elevated endothelial TNAP on coronary atherosclerosis. In addition, we aimed to examine endogenous TNAP activity