INTRODUCTION Chronic Obstructive Pulmonary Disease (COPD) is characterized by progressive and hardly reversible obstruction of the airways, which basically affects the small airways (chronic obstructive bronchiolitis), variably associated with destruction of the pulmonary parenchyma (emphysema). 10%
- In vitro fertilization (IVF) is an important tool for those couples with difficulty conceiving or maintaining a pregnancy. In the United States, infants conceived with IVF account for approximately 1.6% of live births.
- Polycystic ovary syndrome (PCOS), a highly prevalent gynecological disease,
This Biomarker trial is designed to prospectively evaluate the hypothesis that the overall survival (OS) time of a subject with newly diagnosed primary GBM tumors, treated by standard of care (SOC), is a function of the CcO enzymatic activity in the tumor (OS; time interval from date of first
Main objectives of the project:
- To evaluate the usefulness of radiofrequency ablation (RFA) to achieve a lower percentage of positive margins.
- To validate clinically the efficacy and safety of the method in breast tumors smaller than < 2 cm.
Specific objectives of the project:
1. To demonstrate
METHODOLOGY:
This study will be composed of 2 parts:
I - CROSS SECTIONAL STUDY The aim of this section is to compare men with different body compositions, fat distribution and exercise capacity with respect to their muscle mitochondrial biogenesis, oxidative damage and energy flux regulator
This is a Phase I Safety Study which investigates the role of PolyMVA as a supplement in grade IV astrocytoma patients. The primary endpoint of this study is safety/tolerability.
This supplement, PolyMVA, is a uniquely formulated combination of minerals, vitamins, and amino acids. The principle
PRIMARY OBJECTIVES:
I. To determine the objective response rate of R-(-)-gossypol in patients with recurrent chemotherapy-sensitive extensive stage small cell lung cancer.
II. To determine the time to disease progression. III. To determine the overall survival. IV. To assess the toxicities
OBJECTIVES:
Primary
- To measure the rates of cellular apoptosis and proliferation at baseline and during chemoradiotherapy with and without celecoxib using biopsy samples from patients with stage II, III, or IV esophageal cancer.
- To determine if an acceptable rate of pathologic complete remission
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