Vulvovaginal Atrophy

no intervention

St. Mary's Health Center

High Tone Pelvic Floor Dysfunction

Retrospective Chart Review to Investigate an Association Between Vulvovaginal Atrophy and High Tone Pelvic Floor Dysfunction (HTPFD)

Becky Lynn, MD

Principal Investigator

St. Louis University

12 patients with Rett syndrome receiving a daily dose of desipramine correlated with the weight :
From 15 to 25 kg : 50 mg ;
From 26 to 35 kg : 75 mg ;
From 36 to 45 kg : 100 mg ;
> 46 kg : 150 mg.

12 patients with Rett syndrome receiving a daily dose of desipramine correlated with the weight :
From 15 to 25 kg : 25 mg ;
From 26 to 35 kg : 50 mg ;
From 36 to 45 kg : 75 mg ;
> 46 kg : 100 mg.

12 patients with Rett syndrome receiving a daily dose of placebo.

Rett Syndrome

Administration of a daily dose of desipramine correlated with the patient's weight :
From 15 to 25 kg : 50 mg ;
From 26 to 35 kg : 75 mg ;
From 36 to 45 kg : 100 mg ;
> 46 kg : 150 mg.

Administration of a high dose of desipramine

Administration of a daily dose of desipramine correlated with the patient's weight :
From 15 to 25 kg : 25 mg ;
From 26 to 35 kg : 50 mg ;
From 36 to 45 kg : 75 mg ;
> 46 kg : 100 mg.

Administration of a low dose of desipramine

Administration of a daily dose of placebo

Administration of a placebo

Assistance Publique - Hopitaux de Marseille

Pilot Study of the Effects of the Desipramine on the Neurovegetative Parameters of the Child With Rett Syndrome

Assistance Publique Hopitaux De Marseille

Patients in this arm will recieve a combination of PCA MO (10 ug/kg/bolus, by request) and continuous infusion of MO (10 ug/kg/h), when visual analog scale (VAS) exeeds 5/10 boluses will be self-administered by the patient.

Patients in this arm will be administered with only boluses of 1.5 mg/bolus of MO, by request.

Post Operative Pain

Patients in this arm will recieve a combination of PCA MO (10 ug/kg/bolus, by request) and continuous infusion of MO (10 ug/kg/h), when visual analog scale (VAS) exeeds 5/10 boluses will be self-administered by the patient. Rescue diclofenac 75 mg IM will be allowed once to help prompt start analgesia instead of opioid titration, and 6h later. No hourly dose limit will be set for the protocols.

a combination of PCA MO and continuous infusion of MO

When visual analog scale [VAS] exeeds 5/10, and after the PACU drug-blinded attending physician had established that the patient is coherent and cooperative, a PCA system will be connected to the patient's IV line. The physician will start device, and deliver the first bolus. The subsequent drug boluses will be self-administered by the patient. Group 2 will be administered with only boluses of 1.5 mg/bolus of MO, by request. Rescue diclofenac 75 mg IM will be allowed once to help prompt start analgesia instead of opioid titration, and 6h later. No hourly dose limit will be set for the protocols.

PCA MO only

Tel Aviv Sourasky medical center

Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain

Effects of Combination of Continuous Intravenous (IV) Infusion Plus Patient-Controlled Analgesia (PCA) of Morphine (MO) vs. IV-PCA MO on Postoperative Pain Control

Prof Avi Weinbrum, Director Post Anesthesia Care Unit

Tel-Aviv Sourasky Medical Center

Memantine

Sex: Female, Male

Region of Enrollment

Standard Clinical Depression Rating Scale. Clinician administered. Scale units are points/numbers. Possible range is 0 to 44 with the latter signifying more severe anxiety

Hamilton Anxiety Scale

Overall Study

Thomas Schwartz

General Anxiety Disorder, Social Anxiety Disorder

Namenda/Memantine

SUNY Upstate Medical University Psychiatry Dept.

A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder

A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder (GAD) or Social Anxiety Disorder (SAD), Who Are Only Partial Responders to Selective Serotonin-Norepinephrine Reuptake Inhibitors (SNRI's) or Selective Serotonin Reuptake Inhibitors (SSRI's).

diazepam/atrophy

High Tone Pelvic Floor Dysfunction

Pilot Study of the Effects of the Desipramine on the Neurovegetative Parameters of the Child With Rett Syndrome

Effects of a Combination of IV-PCA With Continuous IV Infusion of MO, Versus IV-PCA MO on Postoperative Pain

A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder

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