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2 rezultatima
Long-lasting single-dose tolerance to neurologic deficits induced by diazepam.
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Prijava Registriraj se
Development of single-dose tolerance to diazepam-induced neurologic deficits was assessed in mice by means of a rotarod test. Diazepam suspended in corn oil was administered orally in doses 5-20 mg/kg. Tolerance was found following a second administration of diazepam 24 h after a first dose. It
Gene expression analysis in the ventral prostate of rats exposed to vinclozolin or procymidone.
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Prijava Registriraj se
Vinclozolin and procymidone are antiandrogens that are thought to share a common androgen receptor (AR) mediated mechanism of action. This assessment is based primarily on morphological, AR binding, and in vitro transcriptional activation studies. Studies designed to evaluate the gene expression
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