Addiction

Prevalence of New Psychoactive Substances Use

Prevalence of New Psychoactive Substances Use Among Outpatient of Addiction Management Clinic in Assiut University Hospital

All participant will subjected to the following:
Special sheet designed for the study in department of neurology and psychiatry at Assiut University hospital asking about spychoactive substance use regarding to type, amount, duration,cause of use, and cause for stoppage.
Addiction severity index Urinary drug screen

AAEsraa

Princible investigator

Assiut University

They received two ml of normal saline intravenously as a placebo

They received (20mg) hyoscine butylbromide (one ml HBB+ one ml saline) intravenously

They received (40mg) hyoscine butylbromide (one ml HBB+ one ml saline) intravenously

Vaginal Delivery

Intravenous administration of hyoscine butylbromide during first stage of labor

hyoscine butylbromide

placebo

Kasr Alainy medical school

Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women

Study the Effect of Intravenous Hyoscine Butylbromide Injection on the Duration and Progress of First Stage Labour in High Risk Women

Ahmed Maged

Assistant professor

Cairo University

Somatostatin (Somatosan, BAG Health Care GmbH, Lich, Germany) was given by intravenous bolus (250 μg) followed by 250 μg/hour and continued for 3 days in group S.

Terlipressin (Glypressin, Ferring GmbH, Kiel, Germany) was started at 2mg bolus injection and followed by 1 mg infusion every 6 hours for 3 days in group T.

Vasoconstrictor Choice on Acute Variceal Bleeding

A decision to use vasoactive drugs (either somatostatin or terlipressin) depended on the favorite of participating attending physicians who were requested to fill out the enclosed questionnaires immediately after the administration of the first dose for further understanding the underlying reason of the chosen medication.

Somatostatin

Terlipressin

Both study groups were administered with 40mg pantoprazole intravenously after EVL for 3 days, and following oral form for 12 days to hasten the process of healing of ulcers induced by ligation.

Pantoprazole

Two experienced endoscopists performed emergent EVL for the enrolled patients with acute EVB. Pneumoactive ligation device (Sumitomo Bakelite Co., Ltd, Tokyo, Japan) and endoscopes (GIF XQ260; Olympus Co. Ltd, Tokyo, Japan) were applied. The targeted varix was suctioned and entrapped by a cap on endoscope. Ligation was aimed at active bleeding sites, red color spots or white nipple signs during the procedure.

Endoscopic variceal ligation

Division of Gastroenterology, Department of Internal Medicine

Vasoactive Drugs in Real World Practice

Short-course Somatostatin Versus Terlipressin Infusion in Combination With Endoscopic Variceal Ligation for the Prevention of Early Esophageal Variceal Rebleeding

Early rebleeding was defined as variceal hemorrhage occurs from day 3 till day 42 after initial bleeding arrest. An episode of clinically significant bleeding is being defined by blood transfusion > 2 units of packed red blood cells.

Very early rebleeding was defined as when acute variceal bleeding occurred from 48 to 120 hours after having controlled of initial acute hemorrhage. An episode of clinically significant bleeding is being defined by blood transfusion > 2 units of packed red blood cells.

Incidence rate of all-cause deaths is documented.

Adverse effects associated with vasoactive agents and endoscopic variceal ligation (> grade I by CTCAE v4.0)

hyoscine/hypersensitivity

Prevalence of New Psychoactive Substances Use

Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women

Vasoactive Drugs in Real World Practice

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