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6 rezultatima
Blast from the past: the aluminum's ghost on the lanthanum salts.
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Hyperphosphatemia is a common serious complication of chronic renal diseases, which needs appropriate continuous treatment in order to avoid ominous side effects. Therefore, oral chelating agents able to avoid phosphate absorption by the gut are mandatory. In the past, Aluminium salts, and more
Lanthanum: new drug. Hyperphosphataemia in dialysis patients: more potential problems than benefits.
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(1) In dialysis patients with chronic renal failure, hyperphosphataemia can cause osteorenal dystrophy, leading to bone pain, fractures and excess cardiovascular mortality. In addition to a low-phosphorus diet and dialysis, phosphorus chelators are usually needed to control blood phosphorus levels.
Involvement of pentylenetetrazole in synapsin I phosphorylation associated with calcium influx in synaptosomes from rat cerebral cortex.
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To determine precisely how pentylenetetrazole (PTZ) is involved in the biochemical processes at the presynaptic nerve terminal, the effect of PTZ, under various conditions, on the phosphorylation of synapsin I (previously called protein I) was investigated, using 32Pi in synaptosomes from rat
Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals.
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Neurosteroid sensitivity of GABA(A) receptor mediated inhibition of the hippocampal dentate granule cells (DGCs) is reduced in animal models of temporal lobe epilepsy. However, the properties and subunit composition of GABA(A) receptors mediating tonic inhibition in DGCs of epileptic animals have
Breakdown of the blood-brain barrier and neuropathological changes induced by Phoneutria nigriventer spider venom.
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The blood-brain barrier (BBB) is responsible for selective flux of substances between blood and brain. The selective permeability of the BBB is crucial for the maintenance of the brain microenvironment homeostasis, and alterations in the barrier may be involved in many pathophysiological processes.
Effects of drugs on neurotransmitter release: experiments in vivo and in vitro.
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Calcium ions play a fundamental role in the release of transmitters in the nervous system. Therefore, drugs capable of modifying Ca2+ transport are useful tools for studying the mechanisms of such release in vivo and in vitro. In this article the action of some of these drugs on motor behavior, as
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