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2 rezultatima
Macelignan inhibits melanosome transfer mediated by protease-activated receptor-2 in keratinocytes.
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Prijava Registriraj se
Skin pigmentation is the result of melanosome transfer from melanocytes to keratinocytes. Protease-activated receptor-2 (PAR-2) is a key mediator of melanosome transfer, which occurs as the melanocyte extends its dendrite toward surrounding keratinocytes that take up melanosomes by phagocytosis. We
Macelignan attenuated allergic lung inflammation and airway hyper-responsiveness in murine experimental asthma.
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OBJECTIVE
Macelignan isolated from Myristica fragrans Houtt. is widely used for spice and flavoring for foods, and has been reported to have anti-inflammatory activity. The aim of this study was to investigate the effects of macelignan on allergic lung inflammation with a murine model of
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