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2 rezultatima
A tyrosine aminotransferase involved in rosmarinic acid biosynthesis in Prunella vulgaris L.
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Prijava Registriraj se
Rosmarinic acid (RA) and its derivants are medicinal compounds that comprise the active components of several therapeutics. We isolated and characterised a tyrosine aminotransferase of Prunella vulgaris (PvTAT). Deduced PvTAT was markedly homologous to other known/putative plant TATs. Cytoplasmic
Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner.
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Lck is a T cell-restricted Src family protein tyrosine kinase that plays pivotal roles in TCR-mediated signaling. We aimed to identify novel agents that could disrupt the molecular interaction of the Src homology 2-domain of Lck (Lck SH2) with its binding partners, with the expectation that this
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