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psoriasis/phosphatase
Veza se sprema u međuspremnik
Stranica 1 iz 145 rezultatima
Lack of association between psoriasis vulgaris and red cell acid phosphatase polymorphism.
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Polymorphism of red cell acid phosphatase (ACP-1; E.C. 3.1.3.2.) has been studied using the Cellogel technique of Martin et al. (1975) in 102 patients with psoriasis and 102 healthy controls. In contrast to two previous reports, no anomalies in distribution of phenotypes were found in patients or in
The protein tyrosine phosphatase, non-receptor type 22 R620W polymorphism does not confer susceptibility to psoriasis in the genetic homogeneous population of Crete.
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Recent whole-genome and candidate-gene association studies in patients with psoriasis (PS) have identified a number of single-nucleotide polymorphisms (SNPs) that predispose to disease with moderate risk. Predisposition to PS is known to be affected by genetic variation in human leukocyte antigen-C
Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis.
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BACKGROUND
Atopic dermatitis (AD) and psoriasis are the 2 most common chronic inflammatory skin diseases. There is an unmet medical need to overcome limitations for transcutaneous drug development posed by the skin barrier.
OBJECTIVE
We aimed to identify a novel transdermal delivery peptide and to
NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.
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NF-κB is constitutively activated in psoriatic epidermis. However, how activated NF-κB promotes keratinocyte hyperproliferation in psoriasis is largely unknown. Here we report that the NF-κB activation triggered by inflammatory cytokines induces the transcription of microRNA (miRNA) miR-31, one of
The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) R620W Functional Polymorphism in Psoriasis.
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UNASSIGNED
Psoriasis is a complex autoimmune disease caused by the interaction of genetic and environmental factors. PTPN22 gene polymorphism has been reported to affect psoriasis susceptibility; however, no data are available for Middle Eastern populations.
UNASSIGNED
The aim of this study was to
[The alkaline phosphatase activity of the blood serum as a factor reflecting the chronic inflammatory process in the skin in generalized forms of psoriasis, neurodermatitis, eczema and trophic ulcers].
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Blood serum alkaline phosphatase (AP) level was found elevated in the patients suffering from eczema, neurodermatitis, eczema with large skin sites involved, and in those with trophic ulcers of various origins, as against normal subjects and reference patients with sarcoidosis and Kaposi's sarcoma.
[Changes in the acid and alkaline phosphatase and acid hyaluronidase activities in skin homogenates in psoriasis].
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[Clinical significance of cytochemical determination of alkaline phosphatase activity in neutrophilic leukocytes from patients with psoriasis].
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Acid phosphatase of neutrophils in peripheral blood of patients with psoriasis.
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[On the ester-splitting and ester-forming ability of the skin surface. Part 3. The behavior of estersplitting enzymes (nonspecific esterases and phosphatases) on the skin surface and under the horny layer in normal and pathological conditions, with special references to acne vulgaris and psoriasis].
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A study of fructose-1,6-diphosphatealdolase, lactatedechydrogenase, leucineaminopeptidase, aspartate- and alanine-transaminase, alkaline phosphatase and cholinesterase in the blood serum of patients with psoriasis.
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[Activity of beta-glucuronidase and acid phosphatase in fractions of granulocytes isolated from PMNL in peripheral blood of patients with psoriasis].
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[Determination of blood phosphates and phosphatases after glucose loading, before and after administration of tolbutamide, in psoriasis and various other dermatological patients].
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[Comparative enzyme histochemical studies using four different slide making methods. II. Demonstration of acid phosphatase and non-specific esterase in psoriasis and the farmer's skin].
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[Studies on carbohydrate metabolism in dermatology. IV. Effects of intravenous sodium pyruvate injection on inorganic blood phosphorus, alkaline phosphatases and pyruvemia in psoriasis and other dermatoses].
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