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Stranica 1 iz 16 rezultatima
Hemorrhagic diabetic retinitis; a method of treatment based on the elevation of plasma albumin by diet.
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Ganciclovir-loaded albumin nanoparticles: characterization and in vitro release properties.
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Ganciclovir is one of the most widely used antiviral drug for the treatment of cytomegalovirus retinitis. Due to its short half-life in the vitreous, frequent administrations are necessary to maintain the therapeutic levels. In this context, the aim of this study was to characterise and in vitro
Plasmapheresis with a substitution solution of human serum protein (5%) versus plasmapheresis with a substitution solution of human albumin (5%) in patients suffering from autoimmune diseases.
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Therapeutic plasma exchange (TPE) has been used extensively for over 2 decades to treat a variety of autoimmune and congenital diseases and is now widely accepted. The primary objective of this study was to compare the clinical efficacy of two plasma exchange preparations, human serum protein (HSP)
Thiol/disulfide homeostasis in retinitis pigmentosa patients.
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The agar-albumin sandwich technique for processing retinal biopsy specimens.
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Retinal biopsy may be useful procedure in the diagnosis of certain cases of infectious retinitis complicated by retinal detachment. The small, delicate pieces of retina obtained by retinal biopsy are difficult to handle and prepare for histologic processing. The tissue is friable, may curl upon
[Isolation and characterization of a retinal antigen inducing experimental autoimmune uveo-retinitis].
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A soluble antigen was extracted from the retinas of different mammals and purified by isoelectric focusing in a sucrose density gradient-ampholine column (LKB, Sweden). The isoelectic point of the molecule is about 5.5, its molecular weight about 55,000 and its electrophoretic mobility with
Blood-retinal barrier breakdown in retinitis pigmentosa: light and electron microscopic immunolocalization.
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Macular edema can contribute to visual loss in the retinitis pigmentosa (RP), but the sites and mechanism of blood-retinal barrier (BRB) breakdown leading to macular edema are not known. An understanding of the mechanisms involved could lead to the design of effective pharmacologic therapy to
Fomivirsen: clinical pharmacology and potential drug interactions.
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Fomivirsen sodium is a 21-base phosphorothioate oligodeoxynucleotide complementary to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, and is a potent and selective antiviral agent for cytomegalovirus retinitis. Following intravitreal administration,
[Tyndallometry with the laser flare cell meter in intraocular inflammation].
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The laser flare-cell meter (LFCM) allows noninvasive, quantitative measurement of aqueous flare in human eyes. In this study we analysed changes in aqueous flare in eyes with various forms of intraocular inflammations. PATIENTS. We examined 100 eyes of 100 patients aged (mean +/- SD) 40.2 +/- 19.8
Nonspecific immunoglobulin E in aqueous humor: evaluation in uveitis.
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The levels of immunoglobulin E (IgE) in aqueous humor (AH) and serum were determined in 74 uveitis patients and 13 control patients with senile cataract. Uveitis patients' levels ranged from less than 0.06 to 460 IU/ml according to the paper radioimmunosorbent test (PRIST; limit of sensitivity, 0.06
Filtration and local synthesis of lacrimal proteins in acquired immunodeficiency syndrome.
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In AIDS the onset of the ocular dry syndrome, characterized by lacrimal hyposecretion and deterioration of the corneal and conjunctival epithelium, generally accompanies the clinical aggravation of immunodepression. The study of serum and lacrimal proteins contributes to our knowledge of the
Lipoproteins in human subretinal fluids.
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The lipids in the subretinal fluid of rhegmatogenous retinal detachment are observed mainly in the albumin position following electrophoresis on agarose film. The lipoprotein in the subchoroidal fluid of the same eye is alpha-lipoprotein. The albumin-like lipoprotein in subretinal fluid has no
Prednisone improves renal function and proteinuria in human immunodeficiency virus-associated nephropathy.
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OBJECTIVE
To determine if prednisone ameliorates the course of human immunodeficiency virus-associated nephropathy (HIV-AN).
METHODS
Twenty consecutive HIV-infected adults with biopsy-proven HIV-AN (n = 17) or clinical characteristics of HIV-AN (n = 3) with serum creatinine concentrations > 177
Effect of phytanic acid on cultured retinal pigment epithelium: an in vitro model for Refsum's disease.
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Refsum's disease (heredopathia atactica polyneuritiformis) is an autosomal recessive retinitis pigmentosa syndrome caused by the excessive deposition of phytanic acid in ocular tissues. It is thought that phytanic acid causes retinal degeneration either by interfering with vitamin A metabolism in
Immunohistochemical localization of blood-retinal barrier breakdown in human diabetics.
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Localization of the site of blood-retinal barrier breakdown in diabetes has been controversial. It has been particularly difficult to make assessments in clinical material where the use of tracer materials may not be practical. In this study, immunohistochemical staining for albumin was performed on
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