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sclerosis/edema

Veza se sprema u međuspremnik
Stranica 1 iz 16 rezultatima

3,4-Dihydrospiro-2H-1,3-benzoxazines and their use in treating edema, abnormal electrolyte retention, and inflammation

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Prijava Registriraj se
This invention is concerned with novel 3,4-dihydrospiro-2H-1,3-benzoxazines having therapeutic utility, processes for their preparation, methods of treating inflammation, edema and autoimmune diseases, and novel pharmaceutical formulations comprising at least one of the novel compounds as active

Methods for treatment of kallikrein-related disorders

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BACKGROUND OF THE INVENTION The invention relates to methods for treating plasma kallikrein-related disorders, such as diseases or conditions associated with increased vascular permeability or astrocyte activation. Such diseases include diabetic retinopathy, macular edema, intracerebral hemorrhage,

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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Prijava Registriraj se
The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Associations of xanthogenates and cyclodextrins, and their use

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The invention is related to association products of xanthates and their use. The association products can be used for chemical syntheses and the production of pharmaceutical formulations. The formulations are suitable as medicaments. The invention is also related to the use of the medicaments

Pyrazoline derivative or tetrahydropyridazine derivative and medicinal use thereof

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TECHNICAL FIELD The present invention relates to a novel 3-phenyl-2-pyrazoline derivative or 3-phenyl-tetrahydropyridazine derivative, as well as to a pharmaceutically acceptable salt thereof. More particularly, the present invention relates to an agent containing the above compound, which can

N,N-substituted cyclic amine derivatives

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INDUSTRIAL FIELD OF THE APPLICATION The present invention relates to novel N,N-substituted cyclic amine compounds useful as a calcium antagonist, particularly as a nerve-selective calcium antagonist, specifically as an agent for treating and improving the diseases against which an inhibitory action

Methods of treating and preventing diseases and disorders of the central nervous system

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BACKGROUND OF THE INVENTION The central nervous system (CNS) of an animal, for example, human, contains several important receptor systems such as the glutamate, acetylcholine, GABA.sub.A, and NMDA receptor systems, and injury to the CNS as well as other diseases and disorders of the CNS could be

Methods of treating and preventing diseases and disorders of the central nervous system

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Prijava Registriraj se
BACKGROUND OF THE INVENTION The central nervous system (CNS) of an animal, for example, human, contains several important receptor systems such as the glutamate, acetylcholine, GABA.sub.A, and NMDA receptor systems, and injury to the CNS as well as other diseases and disorders of the CNS could be

Substituted saturated aza heterocycles as inhibitors of nitric oxide synthase

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CROSS REFERENCE TO RELATED APPLICATION The present invention is based on, and claims priority from 60/008,390, filed Dec. 8, 1995. BACKGROUND OF THE INVENTION This application is directed to inhibitors of nitric oxide synthase, and in particular substituted azacycle derivatives. Nitric Oxide in

Cyclic amidine analogs as inhibitors of nitric oxide synthase

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BACKGROUND OF THE INVENTION This application is directed to inhibitors of Nitric oxide synthase, and in particular cyclic amidines. Nitric Oxide in Biology. The emergence of nitric oxide (NO), a reactive, inorganic radical gas as a molecule contributing to important physiological and pathological

Aminoadamantane derivatives as therapeutic agents

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BACKGROUND OF THE INVENTION Certain adamantane derivatives have been used to treat illnesses. Rimantadine (1-(1-aminoethyl)adamantane) is used for the prophylaxis and treatment of influenza in humans. Amantadine has been used for the treatment of both influenza and Parkinson's disease (Schwab et

Aminoadamantane derivatives as therapeutic agents

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Prijava Registriraj se
BACKGROUND OF THE INVENTION Certain adamantane derivatives have been used to treat illnesses. Rimantadine (1-(1-aminoethyl)adamantane) is used for the prophylaxis and treatment of influenza in humans. Amantadine has been used for the treatment of both influenza and Parkinson's disease (Schwab et

Aminoadamantane derivatives as therapeutic agents

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Prijava Registriraj se
BACKGROUND OF THE INVENTION Certain adamantane derivatives have been used to treat illnesses. Rimantadine (1-(1-aminoethyl)adamantane) is used for the prophylaxis and treatment of influenza in humans. Amantadine has been used for the treatment of both influenza and Parkinson's disease (Schwab et
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