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7 rezultatima
The efficacy of corn oil of patients with coronary athero sclerosis.
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The favorable effect of style of Zea mays L. on streptozotocin induced diabetic nephropathy.
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The effectivity of water extract from the style of Zea mays on diabetic nephropathy was investigated in the development of new natural medicinal resources. Streptozotocin (STZ) induced diabetic rats were used to evaluate the therapeutic effect of the style. Urinary albumin excretion and creatinine
Kolaviron protects the brain in cuprizone-induced model of experimental multiple sclerosis via enhancement of intrinsic antioxidant mechanisms: Possible therapeutic applications?
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Multiple sclerosis is a demyelinating condition of the central nervous system which commonly affects young adults. Kolaviron, a biflavonoid isolate of Garcinia kola, has been used in experimental studies which explored its anti-oxidative, anti-inflammatory and anti-genotoxic properties. This work
Kolaviron Protects the Prefrontal Cortex and Hippocampus against Histomorphological and Neurobehavioural Changes in Cuprizone Model of Multiple Sclerosis.
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Background
This study explored the efficacy of kolaviron-a biflavonoid complex isolated from the seeds of Garcinia kola-in protecting against cuprizone (CPZ)-induced demyelination in both the prefrontal cortex and the hippocampus of Wistar rats.Targeted excision of VCP R155H mutation by Cre-LoxP technology as a promising therapeutic strategy for valosin-containing protein disease.
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Inclusion body myopathy associated with Paget's disease of the bone and frontotemporal dementia is attributed to mutations in the valosin-containing protein (VCP) gene, mapped to chromosomal region 9p13.3-12. Affected individuals exhibit scapular winging and die from progressive muscle weakness and
Nephrotoxic effects of long-term carbon tetrachloride administration in rats.
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Rats were given biweekly injections of carbon tetrachloride for up to 34 weeks to investigate the long-term effects on the kidney. Nephrotoxicity was manifest by an increase in urinary protein and albumin excretion as compared with the values in control rats receiving corn oil. Differences in
Signaling pathways modulated by fish oil in salt-sensitive hypertension.
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Although many studies have indicated that fish oil (FO) improves cardiovascular risk factors and reduces histopathological manifestations of injury in experimental renal injury models, potential mechanisms underlying this protective effect have not been adequately defined. The objective of this
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