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15 rezultatima
Cytotoxicity of triterpenoid saponins. Part 1: Activities against tumor cells in vitro and hemolytical index.
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Genuine saponins from Solidago virgaurea L., Heteropappus altaicus (Willd.) Novopokr., H. biennis (Ldb.) Tamamsch., and Helianthus annuus L. (Asteraceae) as well as related carbohydrate modified glycosides of polygalacic acid and echinocystic acid were investigated in view of their structure related
Antineoplastic activity of Solidago virgaurea on prostatic tumor cells in an SCID mouse model.
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Solidago virgaurea (goldenrod) has traditionally been used as an anti-inflammatory herbal medicine for the treatment of various symptoms, including prostatic diseases. The plant has also been reported to have antibacterial, spasmolytic, and carminative properties. During the course of our screening
[Mathematical and graphical evaluation of manometric measurements on metabolism using an electronic computer. Example: respiration and glycolysis in brain tumor sections, as influenced by Solidago extract].
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Inactivation by electron radiation of the capacity of goldenrod polysaccharide to induce vacuolization in ascites tumor cells.
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The anti-inflammatory modulatory role of Solidago chilensis Meyen in the murine model of the air pouch.
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The aim of this study was to investigate the anti-inflammatory efficacy of an aqueous extract (AE), and its butanolic (BuOH) and aqueous residual (AR) fractions, derived from the rhizome of Solidago chilensis in inflammation caused by carrageenan in mice. Solidago chilensis Meyen rhizome was
Anti-inflammatory evaluation of Solidago chilensis Meyen in a murine model of pleurisy.
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The aim of this study was to investigate the anti-inflammatory effects and the mechanism of action of the aqueous extracts obtained from rhizomes, leaves and inflorescences of Solidago chilensis in the mouse model of pleurisy. The extracts were prepared by infusion and were lyophilized.
RESULTS
The
Inhibitory effect of cis-dehydromatricaria ester isolated from Solidago altissima on the growth of mammalian cells.
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A cell growth inhibitory substance was isolated from Solidago altissima, which is known as a naturalized weed. The data of infrared spectrum, proton and carbon-13 nuclear magnetic resonance spectrum, and mass spectrum were identical with those of cis-dehydromatricaria ester. The compound inhibited
Chemical composition and antiproliferative effect of essential oils of four Solidago species (S. canadensis, S. gigantea, S. virgaurea and S.× niederederi)
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There is a growing interest in the research of natural products with potent activity in the prevention and treatment of diseases. Thereby, essential oil phytochemicals have demonstrated broad bioactivities. This study highlights the chemical composition of essential oils obtained from the leaves and
Immunomodulatory and antitumoral effects of triterpenoid saponins.
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Genuine saponins of Solidago virgaurea L., Heteropappus altaicus (Willd.) Novopokr., Heteropappus biennis (Ldb.) Tamamsch. and Helianthus annuus L. (Asteraceae) as well as related carbohydrate modified glycosides of polygalacic acid and echinocystic acid and some commercial available triterpenoid
Antidiabetic and hypolipidemic potentials of Solidago virgaurea extract in alloxan-induced diabetes type 1.
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Objectives: The aim of the current study is to investigate the antidiabetic and hypolipidemic potentials of Solidago virgaurea extract in alloxan-induced diabetic rats.Materials and methods: Alloxan-induced diabetic rats were orally administered a dose of Solidago
Phytochemical constituents of the aerial parts from Solidago virga-aurea var. gigantea.
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The chromatographic separation of the MeOH extract of the aerial parts of Solidago virga-aurea var. gigantea M(IQ) (Compositae) led to the isolation of six terpenoids and four phenolic compounds, trans-phytol (1), ent-germacra-4(15),5,10(14)-trien-1alpha-ol (2), beta-amyrin acetate (3),
Pharmacological reports about gastroprotective effects of methanolic extract from leaves of Solidago chilensis (Brazilian arnica) and its components quercitrin and afzelin in rodents.
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Solidago chilensis Meyenmost (Asteraceae), popularly known as "Brazilian arnica" or "arnica-do-campo," is widely used in the folk medicine to treat gastric disorders. Based on this, the gastroprotective activity of S. chilensis methanolic extract was investigated. Besides, a phytochemical study
Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells.
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Although cancer cells often harbor supernumerary centrosomes, they form pseudo-bipolar spindles via centrosome clustering, instead of lethal multipolar spindles, and thus avoid cell death. Kinesin-14 HSET/KIFC1 is a crucial protein involved in centrosome clustering. Accordingly, a compound that
Nutraceutical Properties of Herbal Infusions from Six Native Plants of Argentine Patagonia.
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Six native plants of South America traditionally consumed in the Patagonian region (southern Argentina and Chile), namely: Adesmia boronioides Hook. f., Apium australe Thouars, Buddleja globosa Hope, Drimys andina (Reiche) R. Rodr. & Quezada, Dysphania multifida L. and Solidago chilensis Meyen were
Multi-channel counter-current chromatography for high-throughput fractionation of natural products for drug discovery.
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A multi-channel counter-current chromatography (CCC) method has been designed and fabricated for the high-throughput fractionation of natural products without complications sometimes encountered with other conventional chromatographic systems, such as irreversible adsorptive constituent losses and
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