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tripterygium/proline
Veza se sprema u međuspremnik
3 rezultatima
[Metabolomics analysis of Tripterygium wilfordii formulation based on theory of detoxicity compatibility].
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Prijava Registriraj se
Tripterygium wilfordii Hook. f. induced-hepatotoxicity was the main limitation for its usage in clinic. Qingluo Tongbi formulation showed obvious attenuation for hepatotoxicity in clinic and fundamental research in vivo. To explore the potential mechanism of the attenuation, we conducted a study on
1H NMR-Based Metabolomics Reveals the Antitumor Mechanisms of Triptolide in BALB/c Mice Bearing CT26 Tumors.
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Prijava Registriraj se
Triptolide, the main active ingredient in Tripterygium wilfordiiHook. f. (Celastraceae), has shown promising effects against a variety of tumors. However, the molecular pharmacological mechanisms explaining the action of triptolide remain unknown. In this study, the CT26 colon tumor
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action.
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BACKGROUND
Celastrol is one of several bioactive compounds extracted from the medicinal plant Tripterygium wilfordii. Celastrol is used to treat inflammatory conditions, and shows benefits in models of neurodegenerative disease, cancer and arthritis, although its mechanism of action is incompletely
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