Biochemical Pharmacology 1990-Sep
Lipid peroxidation caused by hyperthermic perfusion of rat liver.
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Abstrè
The data presented support the premise that hyperthermia-induced hepatocellular injury is the end result of lipid peroxidation. Evidence for lipid peroxidation is the formation of diene conjugates and the decrease in microsomal P450 and glucose-6-phosphatase activity during hyperthermic liver perfusion.