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Ukrains'kyi biokhimichnyi zhurnal (1999 )

[Study of the interaction of main potato glycoalkaloids in inhibition of immobilized butyryl cholinesterase].

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V M Arkhypova
S V Dziadevych
N Jaffrezic-Renault
C Martelet
O P Soldatkin

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Abstrè

The interaction of main potato glycoalkaloids alpha-solanine and alpha-chaconine in inhibition of horse serum butyryl cholinesterases immobilized on the pH-sensitive field-effect transistors has been investigated. The method of isobol diagram of Loewe and Muishnek has been used for interpretation of results. It has been shown the alpha-chaconine inhibits the immobilized bytyryl cholinesterases more strongly than alpha-solanine, and their mixture has the addition effect.

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