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Zhongguo Zhongyao Zazhi 2003-Dec

[Study on the anticancer activities (in vivo) of the extract from Citrus reticulata Blanco and its influence on sarcoma-180 cells cycle].

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Shi-hui Qian
Yi-xian Wang
Nian-yun Yang
Li-hong Yuan

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Abstrè

OBJECTIVE

To study the anticancer activity of the extract from Citrus reticulata in vivo.

METHODS

Anticancer activities were tested with tumor model in vivo (Sarcoma-180 cells, Heps cells, EAC cells implanted in mice).

RESULTS

The extract from Citrus reticulata showed marked anticancer activities on Sarcoma-180 cells and Heps cells implanted in mice, had no marked anticancer activities on EAC cells implanted in mice and induced apoptosis of Sarcoma-180 cell.

CONCLUSIONS

The extract from Citrus reticulata will have promising prospects as an anticancer Chinese medicine, but further studies will be needed.

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