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Patologicheskaya Fiziologiya i Eksperimentalnaya Terapiya

[The use of a vitamin and metabolite complex for correcting the disorders in systemic and organ hemodynamics during liver resection under conditions of acute blood loss].

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A N Shcherban'
S I Korkhov
N V Nazarov
N M Krivitskiĭ
V V Kislukhin
S V Kopytov
I G Kholodov

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Abstrè

The efficacy of some infusion media, vitamins, and metabolites in resection of the liver in acute blood loss was studied in experiments on dogs. Inclusion of vitamins B1, B2, and B6, lipoic acid, calcium pantothenate, nicotinamide, solution of alpha-glutamate and gamma-aminobutyric acid (aminalone) in the infusion led to a sharp increase of myocardial contractility, increase of cardiac output and total hepatic blood flow, normalization of biochemical blood values, and restoration of the activity of hepatocyte enzymes.

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