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alpinia galanga/albumin
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Multispectroscopic and molecular modeling approach to investigate the interaction of flavokawain B with human serum albumin.
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Interaction of flavokawain B (FB), a multitherapeutic flavonoid from Alpinia mutica with the major transport protein, human serum albumin (HSA), was investigated using different spectroscopic probes, i.e., intrinsic, synchronous, and three-dimensional (3-D) fluorescence, circular dichroism (CD), and
Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney.
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BACKGROUND
A number of dysregulated miRNAs have been identified and are proposed to have significant roles in the pathogenesis of type 2 diabetes mellitus or renal pathology. Alpinia oxyphylla has shown significant anti-inflammatory properties and play an anti-diabetes role. The objective of this
Protective effect of Alpinia galanga in STZ induced diabetic nephropathy.
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The activity of the alcoholic extract of the rhizomes of Alpinia galanga was studied for the treatment of diabetes-induced nephropathy in rats. Wistar rats received a single intraperitoneal streptozotocin injection (60 mg kg(-1) b.wt.) to induce diabetes. Rats were considered diabetic if blood
Anti-diabetic effect of Alpinia oxyphylla extract on 57BL/KsJ db-/db- mice.
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Diabetes mellitus is characterized by high blood glucose levels. Increased levels of reactive oxygen species (ROS) may disrupt insulin signaling and result in insulin resistance. The Alpinia oxyphylla extract (AOE) possesses powerful antioxidant activity and may therefore inhibit the development of
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