anthrone/gin diare

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A purgative action of barbaloin is induced by Eubacterium sp. strain BAR, a human intestinal anaerobe, capable of transforming barbaloin to aloe-emodin anthrone.

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Orally administered barbaloin (100 mg/kg) did not induce any diarrhea in male Wistar rats, in spite of severe diarrhea with sennoside B (40 mg/kg). Also, in gnotobiote rats mono-associated with Peptostreptococcus intermedius, a human intestinal anaerobe capable of reducing sennidins to rhein

[Study on difference of functional components content of different Rheum tanguticum variation type].

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Rheum tanguticum from the same area was divided into 8 types of variation according to the plant morphology, content differences of free anthraquinones, combined anthraquinones, double anthrone were studied. The results showed that the functional components of different variation types were

Quantitation of fecal carbohydrate excretion in patients with short bowel syndrome.

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We performed inpatient balance studies in 11 patients to evaluate the role of carbohydrate malabsorption in the pathogenesis of the diarrhea seen in short bowel syndrome. Stool weight, total reducing substance as measured by Clinitest, and total fecal carbohydrate as measured by anthrone were

New cascarosides from Rhamnus purshiana and fragmentation studies of the class by ion trap mass spectrometry.

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BACKGROUND Anthrone and oxanthrone are important anthraquinone derivatives present in medicinal plants which are used in therapeutics as laxatives. Some of these plants need to be stored at least one year before they can be used in order to oxidize anthrones into oxanthrones, so to avoid severe

Studies of aloe. V. Mechanism of cathartic effect. (4).

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Aloe-emodin-9-anthrone(AE-anthrone), produced from barbaloin in the rat large intestine, caused not only an increase in the intestinal water content but also stimulated mucus secretion. This might play an important role in the occurrence of diarrhea. It was demonstrated that the amount of

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