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anticancer/atrophy
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Synthesis and uses of new ascorbic acid derivatives which have anti-oxidant and anti-cancer activities
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to new hydrophobic ascorbic ester compounds, which are synthesized by linking ascorbic acid either wit monomer prostaglandin B.sub.2 or with oligomeric derivatives of prostaglandin B.sub.2, as well as to methods of
Substituted N'-pyrrolo[1,2-a]quinoxalin-4-yl-hydrazides as anti-cancer agents
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FIELD OF THE INVENTION
The present invention relates to therapeutic compounds for treatment of cancer and disorders associated with angiogenesis function. More specifically, the invention relates to novel compounds and their uses in treating cancer such as leukemia, non-small cell lung cancer, colon
Methods of treatment of androgenic steroidal hormone dependent cancer with auger electron-emitting nucleoside analogs
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BACKGROUND
Locally advanced or locally invasive solid tumors are primary cancers that have extensively invaded or infiltrated into the otherwise healthy tissues surrounding the site where the tumor originated. Locally advanced tumors may arise in tissues throughout the body, but unlike early stage
Chlorin e6 derivative and pharmaceutically acceptable salt thereof and process for preparing and use of the same
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TECHNICAL FIELD
The present application relates to the medicine field, specifically to a new chlorin photosensitizer, chlorin e6 ether amino acid derivatives and pharmaceutically acceptable salt thereof, process for preparing and use in preparing anti-tumor drugs, etc.
BACKGROUND OF THE
Benzonaphthalene derivatives, a process for their preparation and their use in therapeutic and cosmetic compositions
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The following non-limiting examples illustrate several examples for the preparation of the active compounds of Formula I according to the present invention, as well as examples of compositions containing these active compounds.
EXAMPLE 1
Methyl ester of 6-(3-methylphenyl)-2-naphthoic acid. Compound
Benzonaphtahalene derivatives, a process for their preparation and their use in therapeutic and cosmetic compositions
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The present invention relates to benzonaphthalene derivatives, to a process for preparing them and to their use in therapeutic and cosmetic compositions.
These new benzonaphthalene derivatives are usefully employed in the topical and systemic treatment of dermatological diseases linked to
Benzonaphthalene derivatives, a process for their preparation and their use in therapeutic and cosmetic compositions
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The present invention relates to benzonaphthalene derivatives, to a process for preparing them and to their use in therapeutic and cosmetic compositions.
These new benzonaphthalene derivatives are usefully employed in the topical and systemic treatment of dermatological diseases linked to
Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions
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The present invention relates to benzonaphthalene derivatives, to a process for preparing them and to their use in therapeutic and cosmetic compositions.
These new benzonaphthalene derivatives are usefully employed in the topical and systemic treatment of dermatological diseases linked to
Benzonaphthalene derivatives and compositions
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The present invention relates to benzonaphthalene derivatives, to a process for preparing them and to their use in therapeutic and cosmetic compositions.
These new benzonaphthalene derivatives are usefully employed in the topical and systemic treatment of dermatological diseases linked to
Phosphinate based inhibitors of matrix metalloproteases
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BACKGROUND OF THE INVENTION
The present invention relates to phosphinate based derivatives which are inhibitors of matrix metalloproteinases or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of a condition selected from the group consisting of arthritis,
Pyridine derivative
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TECHNICAL FIELD
The present invention relates to a pyridine derivative having an ability to act as a neurotrophic factor and a salt thereof.
BACKGROUND ART
It has been suggested that in Alzheimer's disease, which has recently been increasing in prevalence, degeneration and dysfunction of cholinergic
Histone deacetylase inhibitors
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TECHNICAL FIELD
This invention relates to enzyme inhibitors, and more particularly to histone deacetylase inhibitors.
BACKGROUND
DNA in the nucleus of the cell exists as a hierarchy of compacted chromatin structures. The basic repeating unit in chromatin is the nucleosome. The nucleosome consists of
Histone deacetylase inhibitors based on trihalomethylcarbonyl compounds
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TECHNICAL FIELD
This invention relates to trihalomethylcarbonyl compounds, and more particularly to trihalomethylcarbonyl compounds that are histone deacetylase inhibitors.
BACKGROUND
DNA in the nucleus of the cell exists as a hierarchy of compacted chromatin structures. The basic repeating unit in
Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
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TECHNICAL FIELD
This invention relates to alpha-ketoepoxide compounds, and more particularly to alpha-ketoepoxide compounds that are histone deacetylase inhibitors.
BACKGROUND
DNA in the nucleus of the cell exists as a hierarchy of compacted chromatin structures. The basic repeating unit in
Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
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TECHNICAL FIELD
This invention relates to alpha-ketoepoxide compounds, and more particularly to alpha-ketoepoxide compounds that are histone deacetylase inhibitors.
BACKGROUND
DNA in the nucleus of the cell exists as a hierarchy of compacted chromatin structures. The basic repeating unit in
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