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Mitomycin compounds having useful anti-tumor activity

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The present invention relates to new mitomycin derivatives having excellent anti-tumour activities and which are of interest in the preparation of anti-tumour compositions. It is known that mitomycins have, in general, excellent anti-tumour activities. Examples of these mitomycins include mitomycin

Antitumor antibiotic macracidmycin

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a new antitumor antibiotic substance and to its production. More particularly, it relates to a new antitumor antibiotic substance designated macracidmycin and to processes for the preparation thereof by the fermentation

Substance AX-2, a process for producing the same and an antitumor composition containing the same

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BACKGROUND OF THE INVENTION This invention relates to a new substance having anti-tumour activity, a process for producing the same by fermentation and an antitumour composition containing the same. It was previously known to produce mitomycin A and/or B by fermentation, which process comprises

Cancer treatment

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TECHNICAL FIELD A method of treating cancer, including carcinomas and sarcomas is claimed. The pharmaceutical composition containing compounds is also claimed. BACKGROUND OF THE INVENTION Cancers are a leading cause of death in animals and humans. The exact cause of cancer is not known, but links

3,5-dichloro-2,4-dimethoxy-6-(trichloromethyl)pyridine having anti-tumor activity

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BACKGROUND OF THE INVENTION The present invention relates to a novel compound, compositions containing the compound, the use of the compound in inhibiting the growth of malignant neoplasms in mammals, and a method of preparing the compound. A number of chemicals that inhibit the growth or otherwise

Antitumor antibiotics MA 144-M.sub.1 and MA 144-M.sub.2

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to new anthracycline glycoside antitumor antibiotics, to processes for their preparation and to pharmaceutical compositions containing them. More, particularly, it relates to new antitumor antibiotics designated MA

Mixture having antitumor activities

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SUMMARY OF THE INVENTION Tice.RTM. substrain BCG is used clinically as an immunotherapeutic agent against superficial bladder cancer. A boiling water extract of this BCG showed antitumor activity against a murine S180 sarcoma model and was fractionated into three fractions, A, B and C, by the use of

Polysaccharide RBS substance and antitumor agent containing same

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a novel polysaccharide RBS substance and antitumor agent containing said substance as the effective component. 2. Description of the Prior Art As is known in the art, polysaccharides are obtained from various sources,

Methods for anti-tumor therapy

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BACKGROUND OF THE INVENTION Approximately twenty percent of deaths from all causes in the United States are cancer-related. Although chemotherapy is a principal means of cancer treatment, the rate at which effective new drugs have become available for use in cancer chemotherapy has not increased

Method of inhibiting leukemias and sarcomas in a mammalian host

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INTRODUCTION The present invention relates generally to a new antineoplastic substance denominated "pancratistatin", its synthetic counterpart and pharmaceutically acceptable derivatives thereof. The invention further comprises methods for obtaining pancratistatin and 7-deoxynarciclasine, procedures

Composition of matter for inhibiting leukemias and sarcomas

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Use of ureidomustine (BO-1055) in cancer treatment

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BACKGROUND OF THE INVENTION Ever since President Nixon's 1971 declaration of "War on Cancer," a set of assumptions has dominated cancer treatment for over 40 years. A war on cancer is a powerfully evocative metaphor that is directly responsible for a counterproductive and even potentially dangerous

Anti-cancer pharmaceutical compositions and methods for treating patients with cancer

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TECHNICAL FIELD The present invention relates to (a) an anti-cancer pharmaceutical composition which contains a thiazolidinedione compound having a peroxisome proliferators activated receptor (PPAR).gamma. activation potency as an active ingredient, and to (b) an anti-cancer pharmaceutical

Anti-cancer drugs, and uses relating for malignant melanoma and other cancers

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FIELD OF THE INVENTION The present invention relates to Selenophene compounds and Selenophene triazene compounds, their geometrical isomeric forms, stereoisomers, configurational isomers, polymorphs, hydrates, solvates and pharmaceutically acceptable salts thereof. The present invention further

Anti-cancer drugs and uses relating thereto for metastatic malignant melanoma and other cancers

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FIELD OF THE INVENTION The present invention relates to triazene analogs of the general formula (I) and formula (II), their tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, and pharmaceutically acceptable salts thereof for the metastatic malignant melanoma and other cancers including

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Herbal & Natural Medicine

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