anticoagulant/atrophy

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Impact of renal function deterioration on adverse events during anticoagulation therapy using non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation.

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Renal function is crucial for patients with non-valvular atrial fibrillation (NVAF) using non-vitamin K antagonist oral anticoagulants (NOAC). The incidence of renal function deterioration during anticoagulation therapy and its impact of adverse events are unknown. In 807 consecutive NVAF patients

Antiplatelet and Anticoagulant Drugs Do Not Affect Visual Outcome in Neovascular Age-Related Macular Degeneration in the BRAMD Trial.

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To determine if use of antiplatelet or anticoagulant (AP/AC) medication influences visual acuity in patients with active neovascular age-related macular degeneration (N-AMD). Retrospective analysis of data from a randomized controlled trial. Setting: Multicenter. Total of 330 patients with active

Massive hemorrhage complicating age-related macular degeneration. Clinicopathologic correlation and role of anticoagulants.

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Reported are 15 cases of age-related macular degeneration (AMD) complicated by massive subretinal and/or vitreous hemorrhage. Clinicopathologic correlation is presented in four of the seven cases studied histopathologically. Salient histologic findings include: subretinal and subretinal pigment

Massive choroidal hemorrhage in age-related macular degeneration: a complication of anticoagulant therapy.

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BACKGROUND Age-related macular degeneration (ARMD) is the leading cause of legal blindness in the elderly, causing profound loss of central vision. METHODS A 90-year-old patient with exudative age-related macular degeneration who had been placed on anticoagulant therapy for pulmonary emboli

Relationship between anticoagulant medication and massive intraocular hemorrhage in age-related macular degeneration.

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BACKGROUND A massive intraocular hemorrhage in the course of age-related macular degeneration (AMD) is a devastating event. We set out to determine the role of anticoagulant therapy prescribed for vascular or cardiac indications in the development of a massive hemorrhage. METHODS A retrospective

Epidemiology of the association between anticoagulants and intraocular hemorrhage in patients with neovascular age-related macular degeneration.

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OBJECTIVE To determine the cumulative incidence and annual incidence of intraocular hemorrhage (subretinal hemorrhage or vitreous hemorrhage) in patients with neovascular age-related macular degeneration (AMD) and association with daily antiplatelet or anticoagulant (AP/AC) medication usage

Association between Antiplatelet or Anticoagulant Drugs and Retinal or Subretinal Hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trials.

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OBJECTIVE To evaluate the association between use of antiplatelet or anticoagulant drugs and retinal or subretinal hemorrhage in participants with neovascular age-related macular degeneration (AMD) in the Comparison of AMD Treatments Trials (CATT). METHODS Cohort study within

[Submacular hemorrhage with retinal detachment due to an overdose of anticoagulant during age-related macular degeneration].

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Case report: sudden painful blindness. Complication of anticoagulant and antiplatelet therapy in patients with disciform macular degeneration.

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[On the effectiveness of the application of anticoagulants in pigmentary retinal degeneration and embolisms and thromboses of the retinal artery].

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Blunt carotid injury. Importance of early diagnosis and anticoagulant therapy.

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OBJECTIVE The incidence, associated injury pattern, diagnostic factors, risk for adverse outcome, and efficacy of anticoagulant therapy in the setting of blunt and carotid injury (BCI) were evaluated. BACKGROUND Blunt carotid injury is considered uncommon. The authors believe that it is

Transcatheter valve-in-valve implantation Edwards Sapien XT in a direct flow valve after early degeneration

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In recent years, the use of bioprosthetic valve (BPV) has increased significantly with both surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) due to reasons such as the advantage of not using anticoagulants. Nevertheless, major disadvantage of all BPV is the

Impact of anticoagulation therapy on valve haemodynamic deterioration following transcatheter aortic valve replacement.

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OBJECTIVE To evaluate the changes in transvalvular gradients and the incidence of valve haemodynamic deterioration (VHD) following transcatheter aortic valve replacement (TAVR), according to use of anticoagulation therapy. RESULTS This multicentre study included 2466 patients (46% men; mean age 81±7

Intracranial haemorrhage in patients treated with direct oral anticoagulants.

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BACKGROUND Direct oral anticoagulants (DOAC) are increasingly used for the prevention and treatment of thromboembolic events. However, only little evidence is available regarding the management of patients who are treated with DOAC and present with potentially life-threatening intracranial

Clinically important drug interactions with anticoagulants. An update.

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Coumarin derivatives combine 3 unfavorable properties which make them prone to potentially life threatening drug-drug interactions: (i) high protein binding; (ii) cytochrome P450 dependent metabolism; and (iii) a narrow therapeutic range. An entire list of drugs which are supposed to interact with

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