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[SURGICAL INTERVENTION IN THE ORAL CAVITY SUPPORTED BY ANTICOAGULANT THERAPY].

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[Coagulant and anti-coagulant systems of the blood before, during and after surgery on the organs of the abdominal cavity].

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Limitations of conventional anticoagulant therapy and the promises of non-heparin based conformational activators of antithrombin.

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An elevated prothrombotic state is a major risk factor for venous thromboembolism, atrial fibrillation and cardiac strokes. The regulation of various coagulation cascade proteases plays an important role in determining a prothrombotic state. Clinically used anticoagulants are inhibitor of enzymes

Energetics of hydrogen bond switch, residue burial and cavity analysis reveals molecular basis of improved heparin binding to antithrombin.

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Antithrombin III (ATIII) is the main inhibitor of the coagulation proteases like factor Xa and thrombin. Anticoagulant activity of ATIII is increased by several thousand folds when activated by vascular wall heparan sulfate proteoglycans (HSPGs) and pharmaceutical heparins. ATIII isoforms in human

Potential use of recombinant hirudin as an anticoagulant in a cardiopulmonary bypass model.

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Recombinant (r) hirudin is a potent thrombin-specific inhibitor derived from the natural hirudin of the leech (Hirudo medicinalis). We have studied the efficacy of r-hirudin compared with heparin in a canine model of cardiopulmonary bypass operations. Two administration regimens were used for

Subepicardial aneurysm after anticoagulant therapy for a mural thrombus following anterior myocardial infarction.

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A subepicardial aneurysm became evident in a male patient after anticoagulant therapy. On admission, it appeared to be an old anterior infarction accompanied by a mural thrombus. After warfarin administration, the thrombus disappeared and an echo-free space emerged outside the apical myocardial

Locally available heparin modulates inflammatory cell recruitment in a manner independent of anticoagulant activity.

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Heparin is known to possess anti-inflammatory properties that in many cases appear to be separable from its anticoagulant activity. Mast cells, located in tissue, are the sole source of endogenous heparin, which may be involved in control of the inflammatory response. The majority of studies of the

[Hemangiolymphangioma of the abdominal cavity complicated with consumption coagulopathy].

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A case of giant hemangiolymphangioma of abdominal cavity is reported. It showed severe bleeding from consumption coagulopathy and secondary fibrinolysis. (Kasabach-Merritt syndrome). A review is made of the production mechanism of coagulation abnormalities that may accompany vascular neoplasias, the

Pulmonary Thromboembolism Presenting as Multiple Pulmonary Cavities.

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A 38 years old male patient presented to the emergency department with acute severe retrosternal chest pain and was found to have pulmonary thromboembolism. The patient developed new necrotic lung cavities each day due to the dissemination of emboli from the thrombus. The cause of thrombus was found

Spontaneous left ventricle cavity thrombus in a patient of systemic lupus erythematosus.

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A 32 year old female with systemic lupus erythematosus having circulating lupus anticoagulant developed a thrombus in the left ventricle cavity, an unusual site. She responded to standard anticoagulant regime.

Identification of herpesvirus types 1-8 in oral cavity of children/adolescents with chronic renal failure.

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The aim of this investigation was to identify the prevalence of herpesvirus types 1-8 in the oral cavity of subjects with chronic renal failure (CRF) and healthy subjects and compare the two groups, and also correlate the presence of the virus with some characteristics of CRF disease (the type of

Maintenance of perioperative antiplatelet and anticoagulant therapy for vitreoretinal surgery.

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BACKGROUND The objective of this study was to prospectively assess the risk of bleeding from vitreoretinal surgery in a continuous unbiased cohort of patients taking unsuspended antiplatelet or anticoagulant therapy. METHODS Prospective hospital-based study. METHODS Eighty-five patients taking

Is low-intensity anticoagulant therapy possible with an open pivot valve?: analysis of its development.

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In 1976, the authors became the codevelopers of the first successful bileaflet heart valve which has become the standard in valvular surgery. However, there still remains a significant rate of thromboembolism and thrombosis which can be attributed to the inherent design of cavities in the pivot

[Non-bacterial thrombotic endocarditis on the bicuspid aortic valve in a 25-year-old male with lupus anticoagulant].

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Non-bacterial thrombotic endocarditis (NBTE) is characterized by presence of sterile vegetations that develop from fibrin and platelets on heart valves. The main conditions predisposing to NBTE are malignancy, autoimmune diseases and other hypercoagulable states. The authors describe a case of a

[Anticoagulant therapy in connection with cardioversion in patients with atrial fibrillation].

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We present data on possibility of anticoagulant therapy in conjunction with electrical cardioversion in patients with atrial fibrillation using novel anticoagulant - dabigatran - and a case of successful lysis of thrombus in the left ventricular cavity at the background of its administration.

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