arachidonic acid/stroke

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Omega 3 and Ischemic Stroke; Fish Oil as an Option

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Introduction and Background According to the Center of Disease Control and Prevention, stroke is the 5th leading cause of mortality in the US, and a leading cause of significant long-term disability where almost 50% of stroke survivors, age 65 and above, suffer from disabling decrease in mobility.

An Observational Registry Study of LUOTAI in Patients With Acute Ischemic Stroke in Vietnam

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STUDY TITLE: A non-interventional, controlled, open-label (blinded assessor), prospective, multicenter, observational registry study to investigate the clinical practices, safety and effectiveness of LUOTAI (Panax notoginseng) injectable lyophilized powder and soft capsules in routine treatment of

Effect of Fish Consumption on Cardiovascular Risk Factors

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1. Introduction Consumption of fish provides a vital contribution to the survival and health of a significant portion of the world's population. Lipids in fish foods consist mainly of long-chain polyunsaturated fatty acids (PUFAs) such as eicosapentaenic acid (EPA, C20:5n-3) and docosahexaenoic acid

Daily Ginger Drinking and Platelet Function

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Herbal medicine products are dietary supplements that people take to improve their health. Many herbs have been used for a long time for claimed health benefits. They are sold as tablets, capsules, powders, beverages, extracts and fresh or dried plants. Herbal medicines have been associated with

Translational Study of the Effects of Neural Mobilization in Patients With Lomboisquiatalgia

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Translational study of the effects of Neural Mobilization in patients with lomboisquiatalgia The spinal nerve injury in humans often results in neuropathic pain characterized by spontaneous burning pain accompanied by allodynia and hyperalgesia [1]. These signs and symptoms occur in the continuous

The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation

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Clopidogrel, ticagrelor and prasugrel are routinely used for platelet inhibition in addition to aspirin in patients after acute coronary syndromes. The platelet inhibition and patient outcomes (PLATO) trial showed that in patients with acute coronary syndromes, ticagrelor significantly reduced the

Lipidomics Screening of Celecoxib in ex Vivo Human Whole Blood Assay - Part B

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Nonsteroidal anti-inflammatory drugs (NSAIDs), selective for inhibition of cyclooxygenase (COX)-2, alleviate pain and inflammation by suppressing COX-2-derived prostacyclin (PGI2) and prostaglandin (PG) E2 (1). However, eight placebo-controlled clinical trials have revealed that NSAIDs, designed to

Impact of Hybrid Coronary Revascularization on Antiplatelet Therapy

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Objective: The effect of antiplatelet therapy is impaired among patients, who recently underwent on-pump coronary artery bypass grafting. The impact of hybrid coronary revascularization using minimal invasive surgical techniques on the antiplatelet effect of aspirin and clopidogrel remains

Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide

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1. BACKGROUND 1.1 PATHOPHYSIOLOGY Despite improved cataract surgery instrumentation and techniques, the incidence of clinical CME remains 1 - 3% following uncomplicated PE/PCIOL. CME remains the most common cause of suboptimal post-operative visual acuity (VA) after uncomplicated PE/PCIOL. 1%

Ocular Surface Microbiome in Dry Eye Patients

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The ocular surface is the first line of defense of the eye, it is therefore where external threats are sensed, and potential insults neutralised. Over the course of evolution, various microbes, especially bacteriae, have come to colonise the ocular surface as commensals. The commensals have a role

Lipidomics Screening of Anti-inflammatory Drugs and Drug Candidates in Vitro - Part A

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Pharmacogenetic and Pharmacokinetic Study of Clopidogrel

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Associations of the Pharmacogenetic and Pharmacokinetic Factors With Clopidogrel Low Response and Clinical Outcome in Patients With Coronary Stent Implantation: a Registration Study Published data linking clopidogrel non-responsiveness to adverse ischaemic events lead to the suggestion that the

Pharmacogenomics of Antiplatelet Response - I

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The main goal of this study is to explore the impact of the PEAR1 genetic variant (rs12041331) on responsiveness to clopidogrel. The investigators will further assess the role of other genetic variants in determining the response to single or dual anti-platelet therapy. Apparently healthy subjects

Butylphthalide for Preventing Restenosis After Intracranial and Extracranial Artery Stenting

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Ischemic stroke is a significant cause of death, most of the patients is caused by atherosclerosis,current treatments include internal medicine medications, interventional treatment and so on,among them, the interventional therapy can make narrow blood vessels blood recovery fastly,and for its small

Effect of Aspirin at the Acute Phase of Cerebral Ischemic Event.

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