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arsenic/dental caries

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Arsenic exposure and oral cavity lesions in Bangladesh.

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OBJECTIVE To evaluate the relationship between arsenic exposure and oral cavity lesions among an arsenic-exposed population in Bangladesh. METHODS We carried out an analysis utilizing the baseline data of the Health Effects of Arsenic Exposure Longitudinal Study, which is an ongoing population-based

Relation of arsenic supplements to dental caries and the periodontal syndrome in experimental rodents.

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Teratogen update: inorganic arsenic.

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BACKGROUND Inorganic arsenic has been used by many laboratories to study the pathogenesis of exencephaly in rodents. These studies, which used predominantly injection exposures, coupled with the paucity of epidemiology data, resulted in the erroneous inference that inorganic arsenic should be

[Teratogenic effects of arsenic on rats].

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OBJECTIVE To further clarify the effects of arsenic on pregnant rats, fetuses, fetal cells and to verify the experimental results in vitro, and to study the developmental toxicity and its mechanisms of arsenic in depth. METHODS Teratogenic methods in vivo combined with scanning electron microscopy

Arsenic trioxide (As(2)O(3)) inhibits peritoneal invasion of ovarian carcinoma cells in vitro and in vivo.

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OBJECTIVE To study the role of arsenic trioxide (As(2)O(3)) in regulating peritoneal invasive activity of ovarian carcinoma cells in vitro and in vivo. METHODS The effects of As(2)O(3) on human ovarian cancer cell lines (3AO, SW626 and HO-8910PM) migration, invasion and adhesion with tumor cells and
OBJECTIVE Arsenic trioxide (As2O3) has been successfully used to treat the patients with acute promyelocyutic leukemia in clinic, and for the experimental studies of liver cancer, colorectal cancer, gastric cancer, etc. The objective of this study was to explore the inhibitory effect of As2O3 on the
The electrochemical reduction of inorganic As on a graphite cathode depends on the current density. We observed that while only inorganic As(III) is reduced to AsH(3) at low current densities, at high current densities both forms of inorganic As are reduced. We describe a unique electrochemical

Autoradiographic studies on the distribution of arsenic in mice and hamsters administered 74As-arsenite or -arsenate.

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Whole-body autoradiography in combination with other determinations of tissue levels of 74As-arsenic in mice, 5 min. to 30 days after intravenous injections of 74As-arsenite (As III) or -arsenate (As V), showed higher organ concentrations and whole-body retention of arsenic in the As III mice as

Effect of arsenic trioxide on human hepatocarcinoma in nude mice.

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OBJECTIVE To study the effect of arsenic trioxide (As(2)0(3)) on human hepatoma cell line BEL-7402 in vivo. METHODS Human hepatoma cell line BEL-7402 cultured in vitro was inoculated into nude mice and arsenic trioxide, 5-Fu and saline were injected into abdominal cavity of the nude mice

Mortality for certain diseases in areas with high levels of arsenic in drinking water.

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Blackfoot disease was prevalent in a limited area on the southwest coast of Taiwan, where artesian well water containing arsenic (median = 0.78 ppm arsenic) had been used for many years. Previous studies of arsenic exposure in the blackfoot disease endemic area have been focused on malignant tumors.

Swelling of vallate papillae of the tongue following arsenic exposure.

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This cross-sectional study was carried out in some selected arsenic contaminated rural areas of Bangladesh to determine any clinical changes in oral cavity, among the arsenic exposed population through drinking water. Total 600 respondents (200 arsenicosis patients, 200 non-patients but having the

An assessment of the developmental toxicity of inorganic arsenic.

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A critical analysis of the literature base regarding the reproductive and developmental toxicity of arsenic compounds, with emphasis on inorganic arsenicals, was conducted. The analysis was stimulated by the great number of papers that have purported to have shown an association between exposure of

Cancers related to exposure to arsenic at a copper smelter.

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OBJECTIVE This is an update of an earlier study on the relation between exposure to arsenic in air and deaths from respiratory cancer. The purpose was to verify earlier findings of a supralinear dose response relation and to examine relations with other cancers, particularly those reported in

Arsenic and Other Geogenic Contaminants in Groundwater - A Global Challenge

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Groundwater is a much safer and more dependable source of drinking water than surface water. However, natural (geogenic) hazardous elements can contaminate groundwater and lead to severe health problems in consumers. Arsenic concentrations exceeding the WHO drinking water guideline of 10 μg/L
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