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arthritis/edema

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method for treating inflammatory or degenerative diseases by administering to an individual a pharmaceutically effective amount of a mixed extract of Cibotii Rhizoma, Ledebouriellae Radix, Achyranthis Radix,

Method of treating arthritis with etodolac

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BACKGROUND OF THE INVENTION Following treatment of adjuvant arthritic rats with the novel antiinflammatory drug etodolac (1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid, Ultradol.RTM.) there was less bone and articular damage than before the start of treatment. Thus after 28 days

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Chimeric and humanized anti-histone antibodies

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FIELD OF THE INVENTION The invention relates to compositions and methods of use of anti-histone antibodies or antigen-binding fragments thereof. In particular embodiments, the antibodies bind to human histones H2B, H3 or H4. The anti-histone antibodies are of use for diagnosis and/or therapy of a

Nucleic acids encoding chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods for treating thrombosis using chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods for treating sepsis using chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods for treating ischemic stroke using chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods of treating rapidly progressive glomerulonephritis using chimeric and humanized anti-histone H4 antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1 SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods of screening for compounds which bind G protein-coupled receptors

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is the 35 U.S.C. .sctn.371 national stage of PCT application PCT/JP2005/007354, filed Apr. 11, 2005, which claims priority to Japanese patent application No. 116725/2004, filed Apr. 12, 2004. The contents of these applications are incorporated

Therapeutic application of Kazal-type serine protease inhibitors

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This is a national stage entry of PCT/EP2008/001009, filed Feb. 11, 2008, which claims priority to EP 07002903.8, filed Feb. 12, 2007, all of which are incorporated herein by reference. The subject of the present invention is, in the most general aspect, the therapeutic application of the Kazal-type

Electrical producing creams

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is broadly concerned with improved electrical producing creams in forms of creams, lotions, gels or solids which are useful in the treatment of a variety of conditions that are ameliorated by increased cell metabolism,
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