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Paj 1 soti nan 17 rezilta yo
Pipecolic acid derivatives of proline threonine amides useful for the treatment of rheumatoid arthritis
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FIELD OF THE INVENTION
Non-peptidic compounds are described for treatment of autoimmune diseases. Of particular interest are pipecolic acid derivatives compounds incorporating a characterizing segment condensed from pipecolic acid, aspartic acid, proline and threonine, or derivatives thereof, which
Therapeutic proline derivatives
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FIELD OF THE INVENTION
This invention relates to proline derivatives useful as pharmaceutical agents, to processes for their production, to pharmaceutical compositions containing them, and to their use for the treatment of the conditions set out below.
BACKGROUND TO THE INVENTION
Gabapentin
Collagen mimetic and method of treating rheumatoid arthritis using same
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a specific collagen mimetic peptide, pharmaceutical compositions containing the peptide, and a method of treating rheumatoid arthritis through the oral administration of the peptide and/or pharmaceutical composition.
2.
Serine protease inhibitors-proline analogs
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Substituted N-arylsulfonyl-proline derivatives as potent cell adhesion inhibitors
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SUMMARY OF THE INVENTION
The compounds of the present invention are antagonists of the VLA-4 integrin ("very late antigen-4"; CD49d/CD29; or .alpha..sub.4.beta..sub.1), the .alpha..sub.4.beta..sub.7 integrin (LPAM-1 and .alpha..sub.4.beta..sub.p), and/or the .alpha..sub.9.beta..sub.1 integrin, and
Immunosupressive analogues and derivatives of succinylacetone
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TECHNICAL FIELD OF THE INVENTION
This invention is in the area of immunology, and specifically relates to immunopharmacology as applied to the development of immunosuppressive drugs that are useful in treating a wide variety of diseases arising from a dysfunctional hyperactive immune system.
Immunosuppressive analogues and derivatives of succinylacetone
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Log In / Enskri
TECHNICAL FIELD OF THE INVENTION
This invention is in the area of immunology, and specifically relates to immunopharmacology as applied to the development of immunosuppressive drugs that are useful in treating a wide variety of diseases arising from a dysfunctional hyperactive immune system.
Immunosuppressive analogues and derivatives of succinylacetone
Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo
Log In / Enskri
TECHNICAL FIELD OF THE INVENTION
This invention is in the area of immunology, and specifically relates to immunopharmacology as applied to the development of immunosuppressive drugs that are useful in treating a wide variety of diseases arising from a dysfunctional hyperactive immune system.
Immunosuppressive analogues and derivatives of succinylacetone
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Log In / Enskri
TECHNICAL FIELD OF THE INVENTION
This invention is in the area of immunology, and specifically relates to immunopharmacology as applied to the development of immunosuppressive drugs that are useful in treating a wide variety of diseases arising from a dysfunctional hyperactive immune system.
Method for treating inflammatory diseases by administering a thrombin inhibitor
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BACKGROUND OF THE INVENTION
This invention relates to methods for treating inflammatory diseases by administration of a thrombin inhibitor.
Anti-inflammatory drugs include non steroidal anti-inflammatory drugs (NSAIDs) which exert anti-inflammatory, analgesic and antipyretic activity. These include
Benzoquinone derivatives
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This invention relates to novel benzoquinone derivatives having inhibitory activities of protocollagen proline hydroxylase, collagen biosynthesis and 5-lipoxygenase.
Protocollagen proline hydroxylase is an enzyme which specifically hydroxylates the proline residues of the protocollagen synthesized
Benzoquinone derivatives and production thereof
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This invention relates to novel benzoquinone derivatives having inhibitory activities of protocollagenproline hydroxylase, collagen biosynthesis and 5-lipoxygenase.
Protocollagen proline hydroxylase is an enzyme which specifically hydroxylates the proline residues of the protocollagen synthesized by
Benzoquinone derivatives and production thereof
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Log In / Enskri
This invention relates to novel benzoquinone derivatives having inhibitory activities of protocollagenproline hydroxylase, collagen biosynthesis and 5-lipoxygenase.
Protocollagen proline hydroxylase is an enzyme which specifically hydroxylates the proline residues of the protocollagen synthesized by
Benzoquinone derivatives and production thereof
Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo
Log In / Enskri
This invention relates to novel benzoquinone derivatives having inhibitory activities of protocollagen proline hydroxylase, collagen biosynthesis and 5-lipoxygenase.
Protocollagen proline hydroxylase is an enzyme which specifically hydroxylates the proline residues of the protocollagen synthesized
Benzoquinone derivatives and production thereof
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Log In / Enskri
This invention relates to novel benzoquinone derivatives having inhibitory activities of protocollagen-proline hydroxylase, collagen biosynthesis and 5-lipoxygenase.
Protocollagen proline hydroxylase is an enzyme which specifically hydroxylates the proline residues of the protocollagen synthesized
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