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arthritis/seizures

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Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto

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BACKGROUND Status epilepticus is a condition in which the brain is in a state of persistent seizure. There is evidence that 30-60 minutes of persistent seizure is sufficient to damage neurons and that such a seizure is unlikely to self-terminate. Status epilepticus survivors may die soon after or

Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto

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BACKGROUND Status epilepticus is a condition in which the brain is in a state of persistent seizure. There is evidence that 30-60 minutes of persistent seizure is sufficient to damage neurons and such a seizure is unlikely to self-terminate. Status epilepticus survivors may die soon after or have

Prostaglandin receptor EP2 antagonists, derivatives, compositions, and uses related thereto

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BACKGROUND Status epilepticus is a condition in which the brain is in a state of persistent seizure. There is evidence that 30-60 minutes of persistent seizure is sufficient to damage neurons and such a seizure is unlikely to self-terminate. Status epilepticus survivors may die soon after or have

Digital electromagnetic pulse generator

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable INCORPORATION-BY-REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISC Not applicable BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to medical equipment for Magnetic Resonance Therapy

Transdermal delivery of medicaments with combinations of cetylated fatty ester penetrant complexes

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates in general to the field of transdermal and dermal drug delivery by using formulations of said compositions including chemical penetrants molecules, polar solvents, cream base, antioxidants and therapeutic

Compositions and methods for the treatment of moderate to severe pain

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PRIORITY The present application claims the benefit of Indian Provisional Patent Application No. 1840/CHE/2012 filed on 10 May 2012 and the International Application No. PCT/IB2013/050924 filed on 4 Feb. 2013, the entire disclosure of which is relied on for all purposes and is incorporated into this

Tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidines as integrin antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel tetrahydroisoquinoline-3-carboxylic acid alkoxyguanidine compounds that are antagonists of alpha V (.alpha.v) integrins, for example .alpha..sub.v.beta..sub.3 and .alpha..sub.v.beta..sub.5 integrins, their

Substituted [1,2,4]triazolo[4,3-a]pyrazines as P2X7 modulators

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CROSS REFERENCE TO RELATED APPLICATIONS This application is a national phase of International Application No. PCT/US2014/027450 filed on Mar. 14, 2014, which claims the benefit of U.S. Provisional Application No. 61/785,478 filed on Mar. 14, 2013, each of which are incorporated herein by reference

Substituted saturated aza heterocycles as inhibitors of nitric oxide synthase

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CROSS REFERENCE TO RELATED APPLICATION The present invention is based on, and claims priority from 60/008,390, filed Dec. 8, 1995. BACKGROUND OF THE INVENTION This application is directed to inhibitors of nitric oxide synthase, and in particular substituted azacycle derivatives. Nitric Oxide in

Cyclic amidine analogs as inhibitors of nitric oxide synthase

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BACKGROUND OF THE INVENTION This application is directed to inhibitors of Nitric oxide synthase, and in particular cyclic amidines. Nitric Oxide in Biology. The emergence of nitric oxide (NO), a reactive, inorganic radical gas as a molecule contributing to important physiological and pathological
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