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atrophy/phosphatase

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Gene encoding vitamin b.sub.6 phosphate phosphatase and use thereof

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This application is the Nation Stage of International Application NO. PCT/EP2003/01575, filed Sep. 23, 2003. The present invention relates to a novel vitamin B.sub.6 phosphate phosphatase (VB6P phosphatase) gene, recombinant microorganisms transformed with a vector having the gene, and a polypeptide

Alkaline and acid phosphatase inhibitors in treatment of neurological disorders

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FIELD OF THE INVENTION The present invention relates to the use of alkaline and acid phosphatase inhibitors in the treatment of neurological disorders. More particularly, the present invention relates to the use of various specific phosphatase inhibitors in the treatment of .beta.-amyloid toxicity
The present invention relates to the use of carprofen in mammals as a means of treating and preventing cartilage and subchondral bone injury and loss in the inflamed joints of such mammals. Such damage to the cartilage and subchondral bone is a natural sequelae of the process of osteoarthritis and

Stimulating nerve growth with immunophilins

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BACKGROUND OF THE INVENTION The immunosuppressant drugs cyclosporin A and FK506 are thought to exert their therapeutic effects by binding to receptor proteins, designated cyclophilins and FK506 binding proteins (FKBP) respectively. When complexed to the immunosuppressant drugs, these binding

Treatment of tauopathies with mGluR5 antagonists

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the treatment of tauopathies and, more specifically, the use of mGluR5 antagonists for the treatment of tau pathologies. 2. Description of the Related Art Indigenous residents and immigrants of the Pacific Island

Direct influences on nerve growth of agents that interact with immunophilins in combination with neurotrophic factors

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BACKGROUND OF THE INVENTION The immunosuppressant drugs cyclosporin A and FK506 are thought to exert their therapeutic effects by binding to receptor proteins, designated cyclophilins and FK506 binding proteins (FKBP) respectively. When complexed to the immunosuppressant drugs, these binding

Pharmaceutical composition for preventing or treating neurodegenerative diseases

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CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority of Korean Patent Applications Nos. KR 10-2015-0100430, filed Jul. 15, 2015 and KR 10-2015-0100481, filed Jul. 15, 2015, the contents of each of which are hereby incorporated by reference into the application. REFERENCE TO A
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