bradycardia/hyoscine

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Comparative study between atropine and hyoscine-N-butylbromide for reversal of detomidine induced bradycardia in horses.

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BACKGROUND Bradycardia may be implicated as a cause of cardiovascular instability during anaesthesia. OBJECTIVE Hyoscine would induce positive chronotropism of shorter duration than atropine, without adversely impairing intestinal motility in detomidine sedated horses. METHODS Ten minutes after

Bradycardia and hypotension during cyclopropane anaesthesia caused by hyoscine as premedication.

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Hyoscine-N-butylbromide premedication on cardiovascular variables of horses sedated with medetomidine.

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OBJECTIVE To evaluate the effects of intravenous (IV) or intramuscular (IM) hyoscine premedication on physiologic variables following IV administration of medetomidine in horses. METHODS Randomized, crossover experimental study. METHODS Eight healthy crossbred horses weighing 330 ± 39 kg and aged 7

Edrophonium-hyoscine butylbromide mixture for reversal of neuromuscular blockade: heart rate changes in infants and children.

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The effectiveness of hyoscine butylbromide in the prevention of edrophonium-induced bradycardia was assessed in 50 infants and children. A mixture of edrophonium (1.0 mg/kg) and either atropine (0.01 mg/kg) or hyoscine butylbromide (0.4 mg/kg) was administered to reverse the effects of tubocurarine.

Dose-response relationships of intravenous hyoscine butylbromide and atropine sulphate on heart rate in healthy volunteers.

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Heart-rate responses to intravenous hyoscine butylbromide, atropine and physiological saline in cumulative dosage regimens have been recorded in six healthy subjects. Atropine sulphate induced bradycardia at low, and tachycardia at higher, dose levels whereas hyoscine butylbromide caused only

Effects of MK-467 hydrochloride and hyoscine butylbromide on cardiorespiratory and gastrointestinal changes induced by detomidine hydrochloride in horses.

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OBJECTIVE To compare the effects of MK-467 and hyoscine butylbromide on detomidine hydrochloride-induced cardiorespiratory and gastrointestinal changes in horses. ANIMALS 6 healthy adult horses. PROCEDURES Horses received detomidine hydrochloride (20 μg/kg, IV), followed 10 minutes later by MK-467

The effects of vagal stimulation and applied acetylcholine on the sinus venosus of the toad.

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1. The effects of vagal stimulation and applied acetylcholine were compared on the isolated sinus venosus preparation of the toad, Bufo marinus. 2. The effects of applied acetylcholine and of low-frequency, or short bursts of high-frequency vagal stimulation were abolished by hyoscine. 3. When

Beta-adrenoceptor antagonists increase sinus arrhythmia, a vagotonic effect.

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The influence of vagal and sympathetic efferent activity on sinus arrhythmia in man has been studied in six healthy subjects by administration of hyoscine butylbromide and/or various beta-adrenoceptor blocking drugs using a microcomputer-linked electrocardiogram system. Sinus arrhythmia was

Analysis of mechanisms responsible for the bradycardic action of naloxone after haemorrhage in the conscious rabbit.

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We have analyzed the efferent mechanisms responsible for the bradycardia that occurs when naloxone (6 mg/kg) is given i.v. to conscious rabbits after acute blood loss of 17-20 ml/kg. Atenolol and hyoscine methyl bromide were given intrapericardially (i.p.c.), singly and in combination, to allow

Cardiovascular responses and lateral hypothalamic self-stimulation: anatomical differentiation and functional significance.

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Heart rate was telemetrically recorded from rats self-stimulating in a two-day shuttle-box. Blood pressure changes to intracranial stimulation (ICS) were determined in acute studies with the same subjects. Stimulus-bound heart rate decreases were found only at sites in the anterodorsal aspect of the

Cardiovascular changes during induction of anaesthesia. Influence of three anticholinergic premedicants.

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The effects on cardiovascular changes during induction of anaesthesia and intubation of routine premedication with three different anticholinergic drugs, atropine, hyoscine, and glycopyrronium, were compared in a double blind trial. Administration of both atropine and hyoscine, whether

Use of nicotine, bradykinin and veratridine to elicit cardiovascular chemoreflexes in unanaesthetized rabbits.

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1. We have characterized in unanaesthetized rabbits the reflex effects of injecting nicotine into the pericardial sac or left atrium on heart rate, arterial pressure, systemic vascular resistance and the amplitude and frequency of respiration. These effects were compared with those of atrial

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