carcinogenesis/protease

Lyen an sove nan clipboard la

Chwazi kalite sòt

Paj 1 soti nan 623 rezilta yo

Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

Secretory leukocyte protease inhibitor (SLPI), 11.7 kDa serine protease inhibitor, is produced primarily in the respiratory tract, but it is often elevated in lung, head/neck and ovarian cancers. SLPI expression in relation to cancer progression, metastasis and invasion has been studied extensively

Estrogen-induced lysosomal proteases secreted by breast cancer cells: a role in carcinogenesis?

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

In an attempt to understand the mechanism by which estrogens stimulate cell proliferation and mammary carcinogenesis, metastatic human breast cancer cell lines (MCF7, ZR75-1) were found to secrete a 52,000 dalton (52K) protein under estrogen stimulation. Following its purification to homogeneity,

Protease inhibitor-induced stabilization of p21(waf1/cip1) and cell-cycle arrest in chemical carcinogen-exposed mammary and lung cells.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

In previous studies, we have shown that human breast and lung carcinoma cells and mouse nontransformed type II lung cells fail to undergo cell-cycle arrest in G(1) phase in response to treatment with hydrocarbon carcinogens but rather accumulate in the S phase with damaged DNA. This situation may

Effect of the synthetic protease inhibitor [N,N-dimethylcarbamoyl-methyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate on carcinogenesis by 3-methylcholanthrene in mouse skin.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

The effect of the potent synthetic protease inhibitor [N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)-phenylacetate] methanesulfate (FOY-305) on skin carcinogenesis in ddY mice was examined over a total observation period of 105 days. Administration of 0.1% FOY-305 in the diet suppressed the

Cell Surface Human Airway Trypsin-Like Protease Is Lost During Squamous Cell Carcinogenesis.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

Cancer progression is accompanied by increased levels of extracellular proteases that are capable of remodeling the extracellular matrix, as well as cleaving and activating growth factors and receptors that are involved in pro-cancerous signaling pathways. Several members of the type II

Keratinocyte-specific onset of serine protease BSSP expression in experimental carcinogenesis.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

Malignant transformation of mouse skin by chemical carcinogens and tumor promoters, such as the phorbol ester 12-O-tetradecanoylphorbol-13-acetate, is a multistage process leading to the formation of squamous cell carcinomas. In an effort to identify target genes whose expression is associated with

Selective DNA-amplification induced by carcinogens (initiators): evidence for a role of proteases and DNA polymerase alpha.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

Inhibitors of DNA polymerase alpha (aphidicolin, phosphonoacetic acid, phosphonoformic acid) efficiently inhibit initiator-induced amplification of SV40 DNA sequences in the SV40-transformed Chinese hamster cell line CO631. Amplification is also inhibited by various protease inhibitors (antipain,

Induction of a novel Ca2+-dependent serine protease in rat liver treated with various promoters of liver carcinogenesis.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

The induction of a novel Ca2+-dependent protease in rat liver treated with various liver promoters, as well as its increase in preneoplastic lesions during liver carcinogenesis, was demonstrated. Six groups of male Fischer 344 rats (150 g body weight) were fed separately diets containing one of the

Inhibition of carcinogen-induced chromosomal aberrations by an anticarcinogenic protease inhibitor.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

It was hypothesized that chemicals- and radiation-induced carcinogenesis might require at least two specific chromosomal events that must coincide within a single target cell: (i) induction of chromosomal changes, possibly mutations, that are recessive and therefore latent in diploid somatic cells

Inhibition of oral carcinogenesis by a protease inhibitor.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

The effect of the Bowman-Birk inhibitor (BBI) and soybean trypsin inhibitor (SBTI) on experimental 7,12-dimethylbenz[a]anthracene [(DMBA) CAS: 57-97-6]-induced oral carcinogenesis in Syrian male hamsters was examined. All treatments were applied topically on both cheek pouches for 20 weeks, and the

Protease inhibitor suppression of colon and anal gland carcinogenesis induced by dimethylhydrazine.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

In the present study, we examined the ability of chymostatin, a highly specific inhibitor of chymotrypsin, to suppress dimethylhydrazine-induced colon carcinogenesis, and the dose-response relationship for an extract of soybeans containing the Bowman-Birk inhibitor (BBI) to suppress

Effects of various preparations of dietary protease inhibitors on oral carcinogenesis in hamsters induced by DMBA.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

We studied the ability of a soybean extract containing the Bowman-Birk protease inhibitor (BBI), referred to as BBI concentrate (BBIC), purified BBI (PBBI), and the chymotrypsin inhibitor from potatoes to suppress oral carcinogenesis in hamsters induced by 7,12-dimethyl-benz[a]anthracene (DMBA).

Prevention of carcinogenesis by protease inhibitors.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

Protease inhibitors are very effective in their ability to suppress carcinogenesis in many different in vivo and in vitro assay systems. One particularly effective protease inhibitor, the soybean-derived Bowman-Birk inhibitor, has been extensively studied in our laboratory. Our results have

Suppression of dimethylhydrazine-induced carcinogenesis in mice by dietary addition of the Bowman-Birk protease inhibitor.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

In the present study the effect of feeding the soybean-derived Bowman-Birk protease inhibitor (BBI) on dimethylhydrazine (DHM)-induced gastrointestinal tract and liver carcinogenesis in mice was examined. In this investigation we found the addition of 0.5 or 0.1% semipurified BBI or 0.1% purified

Promoter hypomethylation of protease-activated receptor 2 associated with carcinogenesis in the stomach.

Se sèlman itilizatè ki anrejistre yo ki ka tradwi atik yo

OBJECTIVE Trypsin acting at protease-activated receptor 2 (PAR2) contributes to a progression of malignant tumors. An abnormal DNA methylation has been recognized as an important molecular mechanism for the genesis of various types of cancers. We attempted to clarify the relationship between the

Antre nan paj
facebook nou an

Herbal & Natural Medicine

Baz done ki pi konplè remèd fèy medsin te apiye nan syans

Travay nan 55 lang
Geri èrbal te apiye nan syans
Remèd fèy rekonesans pa imaj
Kat entèaktif GPS - tag zèb sou kote (vini byento)
Li piblikasyon syantifik ki gen rapò ak rechèch ou an
Search remèd fèy medsin pa efè yo
Izeganize enterè ou yo ak rete kanpe fè dat ak rechèch la nouvèl, esè klinik ak rive

Tape yon sentòm oswa yon maladi epi li sou remèd fèy ki ta ka ede, tape yon zèb ak wè maladi ak sentòm li itilize kont.
* Tout enfòmasyon baze sou rechèch syantifik pibliye