cineole/hypersensitivity

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Characteristics, clinical effect profile and tolerability of a nasal spray preparation of Artemisia abrotanum L. for allergic rhinitis.

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A nasal spray formulation containing an extract of Artemisia abrotanum L. was developed for therapeutic use in patients with allergic rhinitis and other upper airway disorders. The nasal spray preparation used contains a mixture of essential oils (4 mg/ml) and flavonols (2.5 microg/ml), of which

Inflammatory edema induced by 1,8-cineole in the hindpaw of rats: a model for screening antiallergic and anti-inflammatory compounds.

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A number of clinically useful drugs were tested for their ability to inhibit the inflammatory edema induced by 1,8-cineole (cineole), a terpenoid oxide, in the hindpaw of rats. Paw edema was measured by plethysmography following subplantar injection of cineole (20 μl/paw). The edema inducing effect

Anti-allergic activity of sesquiterpenes from the rhizomes of Cyperus rotundus.

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From the 70% ethanol extract of the rhizomes of Cyperus rotundus (CRE), several major constituents including the sesquiterpene derivatives (valencene, nootkatone, and caryophyllene α-oxide), monoterpenes (β-pinene, 1,8-cineole, and limonene) and 4-cymene were isolated and examined for their

Tea tree oil: contact allergy and chemical composition.

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In this article, contact allergy to, and the chemical composition of, tea tree oil (TTO) are reviewed. This essential oil is a popular remedy for many skin diseases, and may be used as neat oil or be present in cosmetics, topical pharmaceuticals and household products. Of all essential oils, TTO has

Interference of myrtol standardized with inflammatory and allergic mediators.

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Myrtol standardized (Gelomyrtol/Gelomyrtol forte) inhibits the activity of 5-lipoxygenase of human basophil and eosinophil leukocytes and the formation of leukotriene C4 as well as 1.8-cineole (eucalyptol). An increase of prostaglandins (PGE2) in mucous membranes of teat cisterns after topical

Assessment of sensitization potential of monoterpenes using the rat popliteal lymph node assay.

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The popliteal lymph node assay (PLNA) has been proposed as a screening test for detecting chemicals with potential of inducing allergic and auto-immune-like reactions in humans. In the present study, we used the rat PLNA to evaluate the immuno-sensitizing potential of 10 monoterpenes found in the

Essential Oils, Part III: Chemical Composition.

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Data on the chemistry of essential oils which have caused contact allergy are provided. The largest group of chemicals found in essential oils consists of terpenes. The number of identified components usually ranges from 100 to 250, but in some oils (lavender, geranium, rosemary) 450 to 500

Peppermint

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Peppermint (Mentha x piperita) contains menthol, menthone, menthyl acetate as major ingredients. Minor ingredients include 1,8-cineole, pulegone, bitter substances, caffeic acid, flavonoids, and tannins. Topical peppermint gel and solutions have been studied for the prevention of pain and cracked

Degradation products of monoterpenes are the sensitizing agents in tea tree oil.

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BACKGROUND Patients using tea tree oil (TTO) topically may become sensitized to this natural remedy. More than 30 cases have been documented in the literature since 1991. OBJECTIVE Freshly distilled, as well as oxidized TTO, some fractions, and single constituents were used for experimental

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